This week is one of the best weeks of the season with plenty of regular season and playoff games to energize the entire nation. There are 23 head-to-head matchups inside the High School Football America 300 national rankings, powered by NFL Play Football, this week.
Follow all of the games below:
Saturday
No. 8 Kakuku (Hawaii) vs. No. 298 Mililani (Hawaii)
Treston McMillan threw for 272 yards, ran for 108 yards as Mililani topped upset Kahuku, 28-21 in the Oahu Interscholastic Association Open Division championship. McMillan threw three scores and ran for a touchdown.
Friday
No. 16 Cocoa (Florida) vs. No. 295 Rockledge (Florida)
Cocoa wrapped-up a 9-1 regular season by shutting-out Rockledge 26-0.
No. 31 Liberty (Arizona) vs. No. 48 Centennial (Arizona)
Liberty will head into the Open Division playoffs as the top-seed after taking-down previously undefeated Centennial 36-17. It was the Lions fourth straight win over their arch-rivals.
No. 34 Edna Karr (Louisiana) vs. No. 153 John Curtis (Louisiana)
The upset of the weekend belongs to John Curtis. On what was expected to be the 622nd win of head coach J.T. Curtis career, the Patriots rolled to a 41-7 victory. The reason it isn’t No. 622, earlier this week, the Louisiana High School Athletic Association said JC had 30 forfeits about a decade ago. The LHSAA counts Coach Curtis as now having 592 wins.
No. 51 Chandler (Arizona) vs. No. 166 Hamilton (Arizona)
The Battle of Arizona Avenue goes to the Chandler with a 49-13 victory Friday night. It is the largest margin of victory in the 24-year old rivalry.
No. 55 Cardinal Gibbons (Florida) vs. No. 209 Clearwater Central Catholic (Florida)
Clearwater Central Catholic completed a perfect 10-0 season with a 34-14 defeat of the two-time defending champs.
Thursday
No. 126 Zachary (Louisiana) vs. No. 182 Catholic (Baton Rouge, Louisiana)
Catholic captured the District 4-5A championship with a 35-28 overtime win over Zachary. Catholic QB Daniel Beale threw two touchdown passes and ran for two scores.
No. 192 Melissa (Texas) vs. No. 293 Lovejoy (Texas)
The District 6-5A championship goes to Lovejoy after the Leopards 28-7 win over Melissa Thursday night. Melissa entered the game scoring 53 points per game.
No. 275 Starkville (Mississippi) vs. No. 284 Tupelo (Mississippi)
Tupelo wrapped-up a 7A Region 2 perfect season with a 36-6 win over arch-rival Starkville.
High School Football America 300 Scoreboard
| Ranking/Team/State | Ranking/Opponent/State | Score |
| No. 1 St. John Bosco (California) | Idle | |
| No. 2 Mater Dei (California) | Idle | |
| No. 3 Bishop Gorman (Nevada) | Coronado (Nevada) | W 63-12 |
| No. 4 Chaminade-Madonna (Florida) | Lakewood (Florida) | W 57-0 |
| No. 5 IMG Academy (Florida) | St. Thomas More (Connecticut) | W 47-0 |
| No. 6 St. Thomas Aquinas (Florida) | Idle | |
| No. 7 St. Joseph’s Prep (Pennsylvania) | Idle | |
| No. 8 Kahuku (Hawaii) | No. 298 Mililani (Hawaii) | W 28-21 |
| No. 9 Mill Creek (Georgia) | Mountain View (Georgia) | W 33-7 |
| No. 10 DeSoto (Texas) | Mansfield (Texas) | W 63-24 |
| No. 11 Buford (Georgia) | Central Gwinnett (Georgia) | W 67-0 |
| No. 12 Colquitt County (Georgia) | Richmond Hill (Georgia) | W 35-3 |
| No. 13 Massillon Washington (Ohio) | Westerville South (Ohio) | W 50-7 |
| No. 14 Sierra Canyon (California) | Idle | |
| No. 15 St. Edward (Ohio) | GlenOak (Ohio) | W 35-0 |
| No. 16 Cocoa (Florida) | No. 295 Rockledge (Florida) | W 26-0 |
| No. 17 American Heritage (Plantation, Florida) | Idle | |
| No. 18 North Shore (Texas) | Kingwood (Texas) | W 55-7 |
| No. 19 Walton (Georgia) | Wheeler (Georgia) | W 42-16 |
| No. 20 Duncanville (Texas) | Mansfield Legacy (Texas) | W 35-3 |
| No. 21 Corona Centennial (California) | Idle | |
| No. 22 Center Grove (Indiana) | Columbus North (Indiana) | W 35-12 |
| No. 23 Good Counsel (Maryland) | Bishop McNamara (Maryland) | W 24-0 |
| No. 24 Norland (Florida) | Killian (Florida) | W 54-0 |
| No. 25 Miami Central (Florida) | Idle | |
| No. 26 Archbishop Hoban (Ohio) | Barberton (Ohio) | W 41-7 |
| No. 27 Westlake (Austin, Texas) | Johnson (Buda, Texas) | W 34-0 |
| No. 28 Central (Phenix City, Alabama) | Prattville (Alabama) | W 48-7 |
| No. 29 Lincoln (San Diego, California) | Idle | |
| No. 30 DeMatha (Maryland) | Idle | |
| No. 31 Liberty (Arizona) | No. 48 Centennial (Arizona) | W 36-17 |
| No. 32 Bergen Catholic (New Jersey) | Idle | |
| No. 33 Serra (San Mateo, California) | St. Ignatius College Prep (California) | W 43-10 |
| No. 34 Edna Karr (Louisiana) | No. 153 John Curtis (Louisiana) | L 41-7 |
| No. 35 Saraland (Alabama) | McGill-Toolen (Alabama) | W 70-27 |
| No. 36 Loyola Academy (Illinois) | Neuqua Valley (Illinois) | W 33-6 |
| No. 37 Mount Carmel (Chicago, Illinois) | Prospect (Illinois) | W 49-15 |
| No. 38 Atascocita (Texas) | No. 239 Summer Creek (Texas) | L 45-28 |
| No. 39 East St. Louis (Illinois) | Normal West (Illinois) | W 54-7 |
| No. 40 Toledo Central Catholic (Ohio) | Defiance (Ohio) | W 41-26 |
| No. 41 St. Frances Academy (Maryland) | National Christian Academy (Maryland) | W 50-7 |
| No. 42 Butler (North Carolina) | Alexander Central (North Carolina) | W 49-7 |
| No. 43 McCallie (Tennessee) | Idle | |
| No. 44 Aledo (Texas) | Brewer (Texas) | W 59-13 |
| No. 45 Carrollton (Georgia) | Idle | |
| No. 46 Edgewater (Florida) | Boone (Florida) | W 42-14 |
| No. 47 Corner Canyon (Utah) | Lone Peak (Utah) | W 35-21 |
| No. 48 Centennial (Arizona) | No. 31 Liberty (Arizona) | L 36-17 |
| No. 49 St. John’s College HS (Washington, DC) | No. 276 Gonzaga (Washington, DC) | W 23-20 OT |
| No. 50 Basha (Arizona) | Perry (Arizona) | W 38-27 |
| No. 51 Chandler (Arizona) | No. 166 Hamilton (Arizona) | W 49-13 |
| No. 52 Long Beach Poly (California) | Vista Murrieta (California) | W 30-21 |
| No. 53 Jones (Orlando, Florida) | Dr. Phillips (Florida) | W 37-0 |
| No. 54 Ben Davis (Indiana) | Pike (Indiana) | W 53-0 |
| No. 55 Cardinal Gibbons (Florida) | No. 209 Clearwater Central Catholic (Florida) | L 34-14 |
| No. 56 Brownsburg (Indiana) | Season Completed | |
| No. 57 Belleville (Michigan) | Saline (Michigan) | W 65-14 |
| No. 58 Katy (Texas) | Katy Taylor (Texas) | W 49-3 |
| No. 59 Gainesville (Georgia) | Jackson County (Georgia) | W 28-0 |
| No. 60 Venice (Florida) | Clearwater Academy International (Florida) | W 53-42 |
| No. 61 Vandegrift (Texas) | Round Rock Westwood (Texas) | W 38-7 |
| No. 62 St. Thomas More (Louisiana) | No. 168 Lafayette Christian Academy (Louisiana) | W 44-40 |
| No. 63 Carlsbad (California) | Idle | |
| No. 64 Destrehan (Louisiana) | Thibodaux (Louisiana) | W 38-12 |
| No. 66 South Oak Cliff (Texas) | Seagoville (Texas) | W 34-13 |
| No. 66 Highland (Arizona) | Desert Ridge (Arizona) | W 12-0 |
| No. 67 Rabun Gap-Nacoochee (Georgia) | Ravenscroft (North Carolina) | W 55-6 |
| No. 68 Mainland (Florida) | No. 141 Lake Mary (Florida) | L 33-0 |
| No. 69 Baylor (Tennessee) | Idle | |
| No. 70 Orange Lutheran (California) | Idle | |
| No. 71 De La Salle (California) | Clayton Valley Charter (California) | W 48-0 |
| No. 72 Folsom (California) | Idle | |
| No. 73 Clay-Chalkville (Alabama) | Idle | |
| No. 74 Thompson (Alabama) | Idle | |
| No. 75 Homestead (Florida) | Idle | |
| No. 76 Bixby (Oklahoma) | Jenks (Oklahoma) | W 31-14 |
| No. 77 Benedictine (Georgia) | Idle | |
| No. 78 Columbus (Miami, Florida) | Idle | |
| No. 79 Male (Kentucky) | Great Crossing (Kentucky) | W 49-15 |
| No. 80 Santa Margarita (California) | Idle | |
| No. 81 Byron Nelson (Texas) | V.R. Eaton (Texas) | W 43-36 |
| No. 82 Lakeland (Florida) | Idle | |
| No. 83 Lincoln (Gahanna, Ohio) | Grove City (Ohio) | W 48-42 |
| No. 84 Pickerington North (Ohio) | Hilliard Darby (Ohio) | W 35-16 |
| No. 85 Providence Day (North Carolina) | Metrolina Christian Academy (North Carolina) | W 57-14 |
| No. 86 South Florence (South Carolina) | Lugoff-Elgin (South Carolina) | W 42-0 |
| No. 87 Grimsley (North Carolina) | North Meckleburg (North Carolina) | W 54-0 |
| No. 88 Northwestern (South Carolina) | Laurens (South Carolina) | W 57-0 |
| No. 89 Imhotep Charter (Pennsylvania) | Benjamin Franklin (Pennsylvania) | W 58-0 |
| No. 90 Archbishop Moeller (Ohio) | No. 229 St. Xavier (Ohio) | W 10-7 |
| No. 91 American Fork (Utah) | Bingham (Utah) | W 42-14 |
| No. 92 Archbishop Spalding (Maryland) | Mount St. Joseph (Maryland) | W 42-3 |
| No. 93 JSerra (California) | Idle | |
| No. 94 Rancho Cucamonga (California) | Edison (Huntington Beach, California) | W 35-14 |
| No. 95 Southlake Carroll (Texas) | Fossil Ridge (Texas) | W 63-0 |
| No. 96 Servite (California) | Valencia (California) | W 48-24 |
| No. 97 Langston Hughes (Georgia) | Paulding County (Georgia) | W 56-9 |
| No. 98 St. Augustine (Florida) | Palatka (Florida) | W 41-6 |
| No. 99 Treasure Coast (Florida) | Idle | |
| No. 100 Seminole (Sanford, Florida) | Idle | |
| No. 101 Rome (Georgia) | Etowah (Georgia) | W 65-0 |
| No. 102 Armwood (Florida) | Lennard (Florida) | W 49-14 |
| No. 103 Buchholz (Florida) | Trinity Catholic (Florida) | W 42-20 |
| No. 104 Bishop McDevitt (Harrisburg, Pennsylvania) | Idle | |
| No. 105 Cibolo Steele (Texas) | Clemens (Schertz, Texas) | W 31-14 |
| No. 106 San Clemente (California) | Idle | |
| No. 107 Booker T. Washington (Miami, Florida) | Idle | |
| No. 108 Mission Viejo (California) | Palos Verdes (California) | W 59-35 |
| No. 109 Archbishop Stepinac (New York) | Chaminade (New York) | W 48-3 |
| No. 110 Creekside (Georgia) | Banneker (Georgia) | W 49-6 |
| No. 111 Cherry Creek (Colorado) | Idle | |
| No. 112 Vero Beach (Florida) | Columbia (Lake City, Florida) | W 31-10 |
| No. 113 Serra (Gardena, California) | Bishop Amat (California) | W 48-14 |
| No. 114 Coconut Creek (Florida) | Idle | |
| No. 115 Skyridge (Utah) | No. 124 Pleasant Grove (Utah) | W 37-30 |
| No. 116 Western (Davie, Florida) | Plantation (Florida) | W 34-14 |
| No. 117 St. Anthony’s (Melville, New York) | No. 120 Cardinal Hayes (New York) | W 42-14 |
| No. 118 Dripping Springs (Texas) | Anderson (Austin, Texas) | W 52-17 |
| No. 119 Iona Prep (New York) | Kellenberg Memorial (New York) | W 49-19 |
| No. 120 Cardinal Hayes (New York) | No. 117 St. Anthony’s (New York) | L 42-14 |
| No. 121 Lake Travis (Texas) | Bowie (Austin, Texas) | W 66-14 |
| No. 122 Lehi (Utah) | Davis (Utah) | W 52-21 |
| No. 123 Oaks Christian (California) | Chaparral (California) | W 41-7 |
| No. 124 Pleasant Grove (Utah) | No. 115 Skyridge (Utah) | L 37-30 |
| No. 125 Grayson (Georgia) | No. 146 Parkview (Georgia) | W 41-14 |
| No. 126 Zachary (Louisiana) | No. 172 Catholic (Baton Rouge, Louisiana) | L 35-28 OT |
| No. 127 Palmetto (Miami, Florida) | Miami Beach (Florida) | W 47-0 |
| No. 128 Longview (Texas) | West Mesquite (Texas) | W 43-0 |
| No. 129 Lake Wales (Florida) | Bartow (Florida) | W 28-3 |
| No. 130 Thomas County Central (Georgia) | Northside (Warner Robins, Georgia) | W 31-16 |
| No. 131 Bryant (Arkansas) | No. 187 Conway (Arkansas) | W 52-33 |
| No. 132 Lee County (Georgia) | Tift County (Georgia) | W 65-14 |
| No. 133 Delbarton (New Jersey) | Idle | |
| No. 134 Ruston (Louisiana) | West Monroe (Louisiana) | W 35-28 |
| No. 135 St. Joseph Regional (Montvale, New Jersey) | Idle | |
| No. 136 Prosper (Texas) | No. 201 McKinney (Texas) | W 24-12 |
| No. 137 Avon (Ohio) | Brecksville-Broadview Heights (Ohio) | W 49-7 |
| No. 138 North Cobb (Georgia) | Osborne (Georgia) | W 31-7 |
| No. 139 Milton (Georgia) | Lambert (Georgia) | W 37-16 |
| No. 140 Rockwall (Texas) | Tyler Legacy (Texas) | W 52-21 |
| No. 141 Lake Mary (Florida) | No. 68 Mainland (Florida) | W 33-0 |
| No. 142 Oakland (Tennessee) | Gallatin (Tennessee) | W 38-3 |
| No. 143 Jesuit (Florida) | Tampa Catholic (Florida) | W 66-35 |
| No. 144 Alcoa (Tennessee) | Chuckey Doak (Tennessee) | W 56-6 |
| No. 145 Denton Guyer (Texas) | Rock Hill (Texas) | W 42-14 |
| No. 146 Parkview (Georgia) | No. 125 Grayson (Georgia) | L 41-14 |
| No. 147 Highland Park (Texas) | Pearce (Texas) | W 45-20 |
| No. 148 Tampa Bay Tech (Florida) | Idle | |
| No. 149 Westlake (Atlanta, Georgia) | Campbell (Georgia) | W 35-0 |
| No. 150 Holy Cross (Louisiana) | East St. John (Louisiana) | W 56-19 |
| No. 151 Christian Brothers College (Missouri) | Marquette (Missouri) | W 44-35 |
| No. 152 Apopka (Florida) | Wekiva (Florida) | W 29-28 |
| No. 153 John Curtis (Louisiana) | No. 34 Edna Karr (Louisiana) | W 41-7 |
| No. 154 Roswell (Georgia) | Alpharetta (Georgia) | W 52-13 |
| No. 155 Pittsburg (California) | Antioch (California) | W 55-6 |
| No. 156 Glenville (Ohio) | Napoleon (Ohio) | W 44-7 |
| No. 157 Auburn (Alabama) | Smiths Station (Alabama) | W 49-8 |
| No. 158 Bartram Trail (Florida) | No. 244 Mandarin (Florida) | W 24-14 |
| No. 159 Brother Martin (Louisiana) | St. Augustine (Louisiana) | W 24-6 |
| No. 160 Crest (North Carolina) | Parkwood (North Carolina) | W 53-0 |
| No. 161 Westfield (Indiana) | Noblesville (Indiana) | W 24-12 |
| No. 162 Hamilton Southeastern (Indiana) | Fishers (Indiana) | W 38-21 |
| No. 163 West (Knoxville, Tennessee) | Daniel Boone (Tennessee) | W 34-0 |
| No. 164 Timpview (Utah) | Brighton (Utah) | W 55-35 |
| No. 165 Valdosta (Georgia) | Idle | |
| No. 166 Hamilton (Arizona) | No. 51 Chandler (Arizona) | L 49-13 |
| No. 167 Liberty (Nevada) | Shadow Ridge (Nevada) | W 35-32 |
| No. 168 Lafayette Christian Academy (Louisiana) | No. 62 St. Thomas More (Louisiana) | L 44-40 |
| No. 169 Granite Hills (El Cajon, California) | Idle | |
| No. 170 Helix (California) | Idle | |
| No. 171 Los Alamitos (California) | Upland (California) | W 35-17 |
| No. 172 Catholic (Baton Rouge, Louisiana) | No. 126 Ruston (Louisiana) | W 35-28 OT |
| No. 173 Clovis North (California) | Idle | |
| No. 174 Hewitt-Trussville (Alabama) | Idle | |
| No. 175 Red Bank Catholic (New Jersey) | Idle | |
| No. 176 Maury (Virginia) | Granby (Virginia) | W 62-0 |
| No. 177 North Crowley (Texas) | Crowley (Texas) | W 56-21 |
| No. 178 Pearl-Cohn (Tennessee) | Lexington (Tennessee) | W 42-2 |
| No. 179 Highland Springs (Virginia) | Hanover (Virginia) | W 30-13 |
| No. 180 Houston County (Georgia) | Veterans (Georgia) | W 42-0 |
| No. 181 Christ Presbyterian Academy (Tennessee) | Christian Academy of Knoxville (Tennessee) | W 42-6 |
| No. 182 Princeton (Ohio) | Hamilton (Ohio) | W 31-14 |
| No. 183 Parkview (Arkansas) | Camden Fairview (Arkansas) | W 42-14 |
| No. 184 De Smet (Missouri) | Hazelwood Central (Missouri) | W 45-6 |
| No. 185 Norcross (Georgia) | North Gwinnett (Georgia) | L 51-41 |
| No. 186 East Central (Indiana) | Greenwood (Indiana) | W 47-0 |
| No. 187 Conway (Arkansas) | No. 131 Bryant (Arkansas) | L 52-33 |
| No. 188 St. Mary’s (Stockton, California) | Idle | |
| No. 189 South Pointe (South Carolina) | Eastside (Taylors, South Carolina) | W 49-7 |
| No. 190 Trinity (Kentucky) | Meade County (Kentucky) | W 52-14 |
| No. 191 Lincoln-Way East (Illinois) | Minooka (Illinois) | W 28-0 |
| No. 192 Melissa (Texas) | No. 293 Lovejoy (Texas) | L 28-7 |
| No. 193 Davison (Michigan) | Grand Blanc (Michigan) | W 24-17 |
| No. 194 Bishop Chatard (Indiana) | Hamilton Heights (Indiana) | W 28-8 |
| No. 195 Byrnes (South Carolina) | Dorman (South Carolina) | W 44-17 |
| No. 196 Hough (North Carolina) | Asheville (North Carolina) | W 51-0 |
| No. 197 Brentwood (Tennessee) | Cane Ridge (Tennessee) | W 28-7 |
| No. 198 Elder (Ohio) | No. 208 Lakota West (Ohio) | L 24-14 |
| No. 199 Weddington (North Carolina) | Providence (North Carolina) | W 42-7 |
| No. 200 Gaffney (South Carolina) | Lexington (South Carolina) | W 47-14 |
| No. 201 McKinney (Texas) | No. 136 Prosper (Texas) | L 24-12 |
| No. 202 Vestavia Hills (Alabama) | Davidson (Alabama) | W 49-14 |
| No. 203 Cathedral (Indiana) | Lawrence North (Indiana) | W 20-3 |
| No. 204 Northwestern (Miami, Florida) | Idle | |
| No. 205 Cardinal Newman (Florida) | No. 279 Palm Beach Central (Florida) | W 28-7 |
| No. 206 Atlantic (Delray Beach, Florida) | Santaluces (Florida) | W 44-28 |
| No. 207 Monarch (Florida) | Deerfield Beach (Florida) | W 14-0 |
| No. 208 Lakota West (Ohio) | No. 198 Elder (Ohio) | W 24-14 |
| No. 209 Clearwater Central Catholic (Florida) | No. 55 Cardinal Gibbons (Florida) | W 34-14 |
| No. 210 Germantown (Tennessee) | West Creek (Tennessee) | W 47-0 |
| No. 211 Don Bosco Prep (New Jersey) | Pope John XXIII (New Jersey) | W 28-17 |
| No. 212 Ocean Springs (Mississippi) | St. Martin (Mississippi) | W 41-0 |
| No. 213 Carthage (Texas) | Idle | |
| No. 214 St. Charles Catholic (Louisiana) | Isadore Newman (Lousiana) | W 28-0 |
| No. 215 De La Salle Collegiate (Michigan) | University of Detroit Jesuit (Michigan) | W 25-6 |
| No. 216 Dillard (Florida) | Blanche Ely (Florida) | L 33-28 |
| No. 217 Chapman (South Carolina) | Crescent (South Carolina) | W 45-0 |
| No. 218 Coppell (Texas) | Plano (Texas) | W 44-0 |
| No. 219 Coffee (Georgia) | No. 220 Ware County (Georgia) | W 28-5 |
| No. 220 Ware County (Georgia) | No. 219 Coffee (Georgia) | L 28-5 |
| No. 221 Cartersville (Georgia) | Idle | L 23-17 |
| No. 222 Benjamin (Florida) | Kings Academy (Florida) | W 48-14 |
| No. 223 Pickerington Central (Ohio) | Upper Arlington (Ohio) | L 23-27 |
| No. 224 Rolesville (North Carolina) | Purnell Swett (North Carolina) | W 62-0 |
| No. 225 Louisville (Mississippi) | Itawamba Agricultural (Mississippi) | W 31-7 |
| No. 226 Brandon (Mississippi) | Northwest Rankin (Mississippi) | W 27-10 |
| No. 227 Mallard Creek (North Carolina) | Marvin Ridge (North Carolina) | W 41-7 |
| No. 228 Oak Grove (Mississippi) | Idle | |
| No. 229 St. Xavier (Ohio) | No. 90 Archbishop Moeller (Ohio) | L 10-7 |
| No. 230 Newton (Georgia) | Archer (Georgia) | W 47-14 |
| No. 231 Lewisville (Texas) | Hebron (Texas) | W 32-10 |
| No. 232 Marist (Georgia) | Riverwood (Georgia) | W 42-6 |
| No. 233 Milford (Ohio) | Mason (Ohio) | L 10-9 |
| No. 234 Raines (Florida) | Westside (Jacksonville, Florida) | W 53-0 |
| No. 235 Anderson (Ohio) | Kings (Ohio) | W 41-3 |
| No. 226 Miramar (Florida) | South Broward (Florida) | W 53-23 |
| No. 237 Woodward Academy (Georgia) | Forest Park (Georgia) | W 45-6 |
| No. 238 Summerville (South Caroilna) | River Bluff (South Carolina) | W 28-3 |
| No. 239 Summer Creek (Texas) | No. 38 Atascocita (Texas) | W 45-28 |
| No. 240 Union (Oklahoma) | Edmond North (Oklahoma) | W 50-14 |
| No. 241 Fort Dorchester (South Carolina) | Socastee (South Carolina) | W 40-14 |
| No. 242 DuPont Manual (Kentucky) | Eastern (Kentucky) | W 58-28 |
| No. 243 St. Xavier (Kentucky) | Oldham County (Kentucky) | W 58-0 |
| No. 244 Mandarin (Florida) | No. 158 Bartram Trail (Florida) | L 24-14 |
| No. 245 Riverside (Jacksonville, Florida) | Ribault (Florida) | W 32-23 |
| No. 246 Trinity Christian Academy (Jacksonville, Florida) | Specially Fit Academy (Florida) | W 47-21 |
| No. 247 C.E. King (Texas) | West Brook (Texas) | W 62-7 |
| No. 248 Lincoln (Tallahassee, Florida) | Florida State University High (Florida) | L 24-22 |
| No. 249 Picayune (Mississippi) | Hancock (Mississippi) | W 49-21 |
| No. 250 Manatee (Florida) | Southeast (Bradenton, Florida) | W 49-0 |
| No. 251 Westfield (Texas) | Aldine (Texas) | W 70-0 |
| No. 252 Bolles School (Florida) | Berkeley Prep (Florida) | L 42-7 |
| No. 253 Allen (Texas) | Little Elm (Texas) | W 66-21 |
| No. 254 Warner Robins (Georgia) | Locust Grove (Georgia) | W 51-21 |
| No. 255 Dickinson (Texas) | Clear Brook (Texas) | W 42-0 |
| No. 256 Monsignor Farrell (New York) | Holy Trinity (New York) | W 36-0 |
| No. 257 Ridge Point (Texas) | Idle | |
| No. 258 Fort Bend Hightower (Missouri City, Texas) | Fort Bend Austin (Texas) | W 49-12 |
| No. 259 Freedom (Woodbridge, Virginia) | St. Michael the Archangel (Virginia) | W 65-20 |
| No. 260 Riverdale (Tennessee) | Green Hill (Tennessee) | W 50-13 |
| No. 261 Douglas County (Georgia) | South Paulding (Georgia) | W 30-7 |
| No. 262 Richland (Texas) | Molina (Texas) | W 51-17 |
| No. 263 Rocklin (California) | Idle | |
| No. 264 Punahou (Hawaii) | Idle | |
| No. 265 Oak Ridge (California) | Idle | |
| No. 266 Mansfield Timberview (Texas) | Adams (Dallas, Texas) | W 55-0 |
| No. 267 Acadiana (Louisiana) | Barbe (Louisiana) | W 57-6 |
| No. 268 Carencro (Louisiana) | Archbishop Shaw (Louisiana) | L 57-50 |
| No. 269 Chambers (North Carolina) | Northwest Guilford (North Carolina) | W 45-20 |
| No. 270 Houston (Tennessee) | Dickson County (Tennessee) | W 47-0 |
| No. 271 Argyle (Texas) | Creekview (Texas) | W 59-0 |
| No. 272 Lamar (Houston, Texas) | Bellaire (Texas) | W 58-0 |
| No. 273 Phoebus (Virginia) | Denbigh (Virginia) | W 77-0 |
| No. 274 Trotwood-Madison (Ohio) | Celina (Ohio) | L 41-25 |
| No. 275 Starkville (Mississippi) | No. 284 Tupelo (Mississippi) | L 36-6 |
| No. 276 Gonzaga (Washington, DC) | No. 49 St. John’s College HS (Washington, DC) | L 23-20 OT |
| No. 277 Cedar Grove (Georgia) | Carver (Atlanta, Georgia) | W 24-14 |
| No. 278 American Leadership Academy (Queen Creek, Arizona) | Queen Creek (Arizona) | W 42-15 |
| No. 279 Palm Beach Central (Florida) | No. 205 Cardinal Newman (Florida) | L 28-7 |
| No. 280 West Linn (Oregon) | West Salem (Oregon) | W 42-7 |
| No. 281 White Knoll (South Carolina) | Cane Bay (South Carolina) | W 28-0 |
| No. 282 Friendship Collegiate (Washington, DC) | Riverdale Baptist (Maryland) | W 18-7 |
| No. 283 Teurlings Catholic (Louisiana) | North Vermilion (Louisiana) | W 49-0 |
| No. 284 Tupelo (Mississippi) | No. 275 Starkville (Mississippi) | W 36-6 |
| No. 285 Batavia (Illinois) | Lincoln-Way Central (Illinois) | W 45-17 |
| No. 286 Edwardsville (Illinois) | Glenbard West (Illinois) | W 48-14 |
| No. 287 Centerville (Ohio) | Springfield (Ohio) | L 17-10 |
| No. 288 San Ramon Valley (California) | Monte Vista (California) | W 34-0 |
| No. 289 Edison (Miami, Florida) | Doral Academy (Florida) | W 41-14 |
| No. 290 Dothan (Alabama) | JAG (Alabama) | W 57-12 |
| No. 291 Enterprise (Alabama) | Percy Julian (Alabama) | W 55-13 |
| No. 292 Fayetteville (Arkansas) | Har-Ber (Arkansas) | W 56-28 |
| No. 293 Lovejoy (Texas) | No. 192 Melissa (Texas) | W 28-7 |
| No. 294 Eau Gallie (Florida) | Melbourne (Florida) | W 50-0 |
| No. 295 Rockledge (Florida) | No. 16 Cocoa (Florida) | L 26-0 |
| No. 296 Boyle County (Kentucky) | Whitley County (Kentucky) | W 41-6 |
| No. 297 Carrollwood Day (Florida) | Gulliver Prep (Florida) | W 41-14 |
| No. 298 Mililani (Hawaii) | No. 8 Kahuku (Hawaii) | W 28-21 |
| No. 299 Salpointe Catholic (Arizona) | Brophy College Prep (Arizona) | L 14-12 |
| No. 300 Lee’s Summit North (Missouri) | Lee’s Summit (Missouri) | W 42-0 |
