It’s another big week of head-to-head matchups inside the High School Football America 300 national rankings, powered by NFL Play Football. There are 49 games this week after 57 head-to-heads last weekend.
Friday Scores
No. 3 Bishop Gorman picked-up a hard-fought 39-35 win over No. 9 Miami Central. Elija Lofton, a Miami (Florida) recruit scored on a 1-yard touchdown run with 24 seconds remaining to give the Gaels the victory to improve to 3-0.
No. 10 Chaminade-Madonna, the defending 1S state champ, had no problems with defending 3S champ Cardinal Gibbons. The Lions roared to a 41-4 win over the No. 23 Chiefs after falling behind 4-0.
No. 14 American Heritage (Plantation, Florida) improves to 2-0 with a 28-6 win over No. 78 Trinity Christian Academy (Jacksonville, Florida).
High School Football America 300 powered by NFL Play Football
| Ranking/Team/State | Ranking/Opponent/State | Score |
| No. 1 St. John Bosco (California) | Friendship Collegiate (Wshington, DC) | W 48-12 |
| No. 2 Mater Dei (California) | No. 112 Creekside (Georgia) | W 62-0 |
| No. 3 Bishop Gorman (Nevada) | No. 9 Miami Central (Florida) | W 39-35 |
| No. 4 IMG Academy (Florida) | No. 16 Thompson (Alabama) | Cancelled |
| No. 5 Buford (Georgia) | No. 140 North Cobb (Georgia) | W 45-28 |
| No. 6 Duncanville (Texas) | No. 186 Rockledge (Florida) | W 44-0 |
| No. 7 St. Thomas Aquinas (Florida) | Fort Myers (Florida) | W 49-0 |
| No. 8 St. Edward (Ohio) | No. 299 Rock Creek Christian (Maryland) | W 42-14 |
| No. 9 Miami Central (Florida) | No. 3 Bishop Gorman (Nevada) | L 39-35 |
| No. 10 Chaminade-Madonna (Florida) | No. 23 Cardinal Gibbons (Florida) | W 41-4 |
| No. 11. St. Joseph’s Prep (Pennsylvania) | No. 156 St. Peter’s Prep (New Jersey) | W 42-0 |
| No. 12 Columbus (Miami, Florida) | Killian (Florida) | W 38-0 |
| No. 13 St. Frances Academy (Maryland) | No. 51 East St. Louis (Illinois) | L 13-7 |
| No. 14 American Heritage (Plantation, Florida) | No. 78 Trinity Christian Academy (Jacksonville, Florida) | W 28-6 |
| No. 15 Colquitt County (Georgia) | Tift County (Georgia) | W 40-2 |
| No. 16 Thompson (Alabama) | No. 4 IMG Academy (Florida) | Cancelled |
| No. 17 Langston Hughes (Georgia) | Butler (North Carolina) | L 30-27 |
| No. 18 North Shore (Texas) | Spring (Texas) | W 53-0 |
| No. 19 DeSoto (Texas) | Idle | |
| No. 20 Bergen Catholic (New Jersey) | No. 98 Iona Prep (New York) | W 38-7 |
| No. 21 Mill Creek (Georgia) | Archer (Georgia) | W 42-7 |
| No. 22 Corona Centennial (California) | Punahou (Hawaii) | W 50-43 |
| No. 23 Cardinal Gibbons (Florida) | No. 10 Chaminade-Madonna (Florida) | L 41-4 |
| No. 24 Mission Viejo (California) | No. 116 Long Beach Poly (California) | L 32-28 |
| No. 25 Westlake (Austin, Texas) | Judson (Texas) | W 47-0 |
| No. 26 Massillon Washington (Ohio) | Mansfield (Ohio) | W 51-10 |
| No. 27 Walton (Georgia) | Idle | |
| No. 28 Basha (Arizona) | No. 213 Highland (Arizona) | L 22-21 |
| No. 29 St. John’s College HS (Washington, DC) | Roosevelt (Washington, DC) | W 37-0 |
| No. 30 Center Grove (Indiana) | No. 199 Trinity (Kentucky) | W 34-7 |
| No. 31 Good Counsel (Maryland) | No. 53 Jones (Orlando, Florida) | W 40-14 |
| No. 32 Archbishop Hoban (Ohio) | Trinity Episcopal (Virginia) | W 34-6 |
| No. 33 DeMatha (Maryland) | St. Michael the Archangel (Virginia) | W 48-7 |
| No. 34 Carrollton (Georgia) | No. 130 Rome (Georgia) | W 33-13 |
| No. 35 Katy (Texas) | No. 97 Atascocita (Texas) | L 42-34 |
| No. 36 Saguaro (Arizona) | Mountain View (Arizona) | W 44-20 |
| No. 37 Lincoln (San Diego, California) | St. Bonaventure (California) | W 49-12 |
| No. 38 Denton Guyer (Texas) | No. 60 Aledo (Texas) | L 48-45 |
| No. 39 Cocoa (Florida) | No. 72 Venice (Florida) | W 31-21 |
| No. 40 Orange Lutheran (California) | Eastside Catholic (Washington) | W 20-0 |
| No. 41 Southlake Carroll (Texas) | Marcus (Texas) | W 57-15 |
| No. 42 Central (Phenix City, Alabama) | Smiths Station (Alabama) | W 51-0 |
| No. 43 Sierra Canyon (California) | Green Valley (Nevada) | W 56-0 |
| No. 44 John Curtis (Louisiana) | Central Lafourche (Louisiana) | W 51-0 |
| No. 45 McCallie (Tennessee) | No. 61 St. Xavier (Ohio) | W 34-11 |
| No. 46 Auburn (Alabama) | Enterprise (Alabama) | L 17-16 |
| No. 47 Mount Carmel (Chicago, Illinois) | Morgan Park (Illinois) | W 22-12 |
| No. 48 Saraland (Alabama) | Murphy (Alabama) | W 54-6 |
| No. 49 Lipscomb Academy (Tennessee) | Briarcrest Christian (Tennessee) | W 42-20 |
| No. 50 Kahuku (Hawaii) | Farrington (Hawaii) | W 48-20 |
| No. 51 East St. Louis (Illinois) | No. 13 St. Frances Academy (Maryland) | W 13-7 |
| No. 52 Edgewater (Florida) | No. 73 Clearwater Academy International (Florida) | W 15-14 |
| No. 53 Jones (Orlando, Florida) | No. 31 Good Counsel (Maryland) | L 40-14 |
| No. 54 Catholic (Baton Rouge, Louisiana) | No. 168 Picayune (Mississippi) | W 36-35 OT |
| No. 55 Serra (San Mateo, California) | No. 101 De La Salle (California) | W 28-0 |
| No. 56 Liberty (Arizona) | O’Connor (Arizona) | W 48-14 |
| No. 57 Toledo Central Catholic (Ohio) | Detroit Catholic Central (Michigan) | W 42-21 |
| No. 58 Belleville (Michigan) | Stevenson (Livonia, Michigan) | W 56-7 |
| No. 59 Bartram Trail (Florida) | Seebreeze (Florida) | W 55-0 |
| No. 60 Aledo (Texas) | No. 38 Denton Guyer (Texas) | W 48-45 |
| No. 61 St. Xavier (Ohio) | No. 45 McCallie (Tennessee) | L 34-11 |
| No. 62 Edna Karr (Louisiana) | Landry-Walker (Louisiana) | W 33-0 |
| No. 63 Oakland (Tennessee) | Haywood (Tennessee) | W 48-6 |
| No. 64 Vandegrift (Texas) | Cedar Park (Texas) | W 41-17 |
| No. 65 Gainesville (Georgia) | Coconut Creek (Florida) | W 30-22 |
| No. 66 Corner Canyon (Utah) | Farmington (Utah) | W 42-3 |
| No. 67 Christian Brothers College (Missouri) | No. 133 Bryant (Arkansas) | L 45-31 |
| No. 68 St. Xavier (Kentucky) | No. 86 Male (Kentucky) | W 20-10 |
| No. 69 Highland Springs (Virginia) | Manchester (Virignia) | W 35-27 |
| No. 70 Armwood (Florida) | Bloomingdale (Florida) | W 55-0 |
| No. 71 Westfield (Texas) | Fort Bend Hightower (Texas) | L 14-9 |
| No. 72 Venice (Florida) | No. 39 Cocoa (Florida) | L 31-21 |
| No. 73 Clearwater Academy International (Florida) | No. 52 Edgewater (Florida) | L 15-14 |
| No. 74 Brownsburg (Indiana) | Franklin Central (Indiana) | W 35-21 |
| No. 75 Norland (Florida) | Carol City (Florida) | W 52-0 |
| No. 76 Roswell (Georgia) | Marietta (Georgia) | W 51-14 |
| No. 77 Destrehan (Louisiana) | Bonnabel (Louisiana) | W 48-7 |
| No. 78 Trinity Christian Academy (Jacksonville, Florida) | No. 14 American Heritage (Plantation, Florida) | L 28-6 |
| No. 79 Archbishop Spalding (Maryland) | Concordia Prep (Maryland) | W 32-31 |
| No. 80 Brother Martin (Louisiana) | Madison Prep Academy (Louisiana) | W 28-0 |
| No. 81 Vero Beach (Florida) | Idle | |
| No. 82 Loyola Academy (Illinois) | Naperville North (Illinois) | W 27-6 |
| No. 83 Northwestern (Miami, Florida) | Jackson (Miami, Florida) | W 63-0 |
| No. 84 Springfield (Ohio) | Trotwood-Madison (Ohio) | L 21-20 |
| No. 85 Folsom (California) | Edison (Stockton, California) | W 48-15 |
| No. 86 Male (Kentucky) | No. 68 St. Xavier (Kentucky) | L 20-10 |
| No. 87 Bixby (Oklahoma) | Har-Bear (Arkansas) | W 75-18 |
| No. 88 Prosper (Texas) | Sachse (Texas) | W 49-13 |
| No. 89 Westlake (Atlanta, Georgia) | No. 223 Cedar Grove (Georgia) | W 46-41 |
| No. 90 South Oak Cliff (Texas) | No. 229 Lancaster (Texas) | W 41-21 |
| No. 91 Lakeland (Florida) | Largo (Florida) | W 28-0 |
| No. 92 JSerra (California) | No. 228 Chaminade (California) | W 41-7 |
| No. 93 Alcoa (Tennessee) | Tottenville (New York) | W 44-6 |
| No. 94 Lake Travis (Texas) | No. 129 Cibolo Steele (Texas) | W 20-10 |
| No. 95 Skyridge (Utah) | No. 232 Bingham (Utah) | W 35-28 |
| No. 96 Providence Day (North Carolina) | Charlotte Catholic (North Carolina) | W 42-7 |
| No. 97 Atascocita (Texas) | No. 35 Katy (Texas) | W 42-34 |
| No. 98 Iona Prep (New York) | No. 20 Bergen Catholic (New Jersey) | L 38-7 |
| No. 99 Union (Oklahoma) | Broken Arrow (Oklahoma) | W 27-17 |
| No. 100 Carlsbad (California) | San Pasqual (California) | W 56-0 |
| No. 101 De La Salle (California) | No. 55 Serra (San Mateo, California) | L 28-0 |
| No. 102 St. Anthony’s (Melville, New York) | Delbarton (New Jersey) | L 34-13 |
| No. 103 West (Knoxville, Tennessee) | Farragut (Tennessee) | W 38-31 |
| No. 104 Cathedral (Indiana) | Penn (Indiana) | W 35-6 |
| No. 105 Cherry Creek (Colorado) | Legacy (Colorado) | W 42-14 |
| No. 106 Lehi (Utah) | Maple Mountain (Utah) | W 37-14 |
| No. 107 St. Ignatius (Ohio) | Pittsburgh Central Catholic | L 47-6 |
| No. 108 Santa Margarita (California) | No. 174 Liberty (Bakersfield, California) | W 34-14 |
| No. 109 Don Bosco Prep (New Jersey) | Erasmus Hall (New York) | W 31-6 |
| No. 110 Grimsley (North Carolina) | Reagan (North Carolina) | W 41-15 |
| No. 111 Chandler (Arizona) | Mountain Ridge (Arizona) | W 49-7 |
| No. 112 Creekside (Georgia) | No. 2 Mater Dei (California) | L 62-0 |
| No. 113 Seminole (Sanford, Florida) | No. 276 Osceola (Kissimmee, Florida) | W 31-6 |
| No. 114 Ben Davis (Indiana) | Pike (Indiana) | W 62-0 |
| No. 115 Hewitt-Trussville (Alabama) | Gadsden City (Alabama) | W 42-27 |
| No. 116 Long Beach Poly (California) | No. 24 Mission Viejo (California) | W 32-28 |
| No. 117 Los Alamitos (California) | No. 171 Timpview (Utah) | W 57-35 |
| No. 118 Mallard Creek (North Carolina) | Idle | |
| No. 119 Hamilton Southeastern (Indiana) | Avon (Indiana) | W 42-23 |
| No. 120 Hoover (Alabama) | No. 222 Oak Grove (Mississippi) | L 28-21 OT |
| No. 121 St. Thomas More (Louisiana) | Comeaux (Louisiana) | W 45-6 |
| No. 122 South Florence (South Carolina) | Orangeburg-Wilkinson (South Carolina) | W 61-0 |
| No. 123 Apopka (Florida) | West Orange (Florida) | W 14-7 |
| No. 124 Northwestern (South Carolina) | Idle | |
| No. 125 Archbishop Moeller (Ohio) | East Central (Indiana) | L 38-28 |
| No. 126 Grayson (Georgia) | No. 159 Fort Dorchester (South Carolina) | W 41-0 |
| No. 127 St. Joseph Regional (Montvale, New Jersey) | Cass Tech (Michigan) | W 49-14 |
| No. 128 Pickerington North (Ohio) | Upper Arlington (Ohio) | W 28-8 |
| No. 129 Cibolo Steele (Texas) | No. 94 Lake Travis (Texas) | L 20-10 |
| No. 130 Rome (Georgia) | No. 34 Carrollton (Georgia) | L 33-13 |
| No. 131 Elder (Ohio) | Springboro (Ohio) | W 28-7 |
| No. 132 Ware County (Georgia) | Baldwin (Georgia) | W 48-20 |
| No. 133 Bryant (Arkansas) | No. 67 Christian Brothers College (Missouri) | W 45-31 |
| No. 134 Lewisville (Texas) | Highland Park (Texas) | L 21-18 |
| No. 135 Booker T. Washington (Miami, Florida) | Idle | |
| No. 136 Glenville (Ohio) | Avon (Ohio) | L 24-16 |
| No. 137 Mainland (Florida) | West Broward (Florida) | W 35-0 |
| No. 138 Benedictine (Georgia) | Westminster (Georgia) | W 27-14 |
| No. 139 Arlington Martin (Texas) | Cedar Hill (Texas) | L 33-2 |
| No. 140 North Cobb (Georgia) | No. 5 Buford (Georgia) | L 45-28 |
| No. 141 Ruston (Louisiana) | No. 256 Warren Easton (Louisiana) | L 20-19 |
| No. 142 Detroit MLK (Michigan) | No. 269 Carmel (Indiana) | L 39-0 |
| No. 143 Inglewood (California) | Idle | |
| No. 144 Western (Davie, Florida) | Idle | |
| No. 145 Oaks Christian (California) | Roosevelt (Eastvale, California) | W 50-14 |
| No. 146 Milton (Georgia) | Idle | |
| No. 147 Lincoln (Gahanna, Ohio) | Olentangy Liberty (Ohio) | W 46-28 |
| No. 148 Parish Episcopal (Dallas, Texas) | Episcopal (Bellaire, Texas) | L 27-20 |
| No. 149 DuPont Manual (Kentucky) | Taft (Ohio) | W 24-8 |
| No. 150 Serra (Gardena, California) | Cathedral (California) | W 47-14 |
| No. 151 Tampa Bay Tech (Florida) | Steinbrenner (Florida) | W 45-0 |
| No. 152 Weddington (North Carolina) | West Forsyth (North Carolina) | W 44-22 |
| No. 153 Kings (Ohio) | Walnut Hills (Ohio) | W 35-12 |
| No. 154 Lee County (Georgia) | Lithia Springs (Georgia) | W 59-12 |
| No. 155 St. Augustine (Louisiana) | McDonogh 35 (Louisiana) | W Forfeit |
| No. 156 St. Peter’s Prep (New Jersey) | No. 11 St. Joseph’s Prep (Pennsylvania) | L 42-0 |
| No. 157 Liberty (Nevada) | Campbell (Hawaii) | W 20-14 |
| No. 158 Pulaski Academy (Arkansas) | Madison-Ridgeland Academy (Mississippi) | W 45-43 |
| No. 159 Fort Dorchester (South Carolina) | No. 126 Grayson (Georgia) | L 41-0 |
| No. 160 McKinney (Texas) | Berkner (Texas) | W 35-14 |
| No. 161 Zachary (Louisiana) | East Ascension (Louisiana) | W 24-7 |
| No. 162 Longview (Texas) | Marshall (Texas) | 48-7 |
| No. 163 Dripping Springs (Texas) | Wagner (San Antonio, Texas) | W 35-14 |
| No. 164 DePaul Catholic (New Jersey) | No. 233 Bishop McDevitt (Harrisburg, Pennsylvania) | L 46-42 |
| No. 165 American Fork (Utah) | Rigby (Idaho) | W 50-7 |
| No. 166 Starkville (Mississippi) | West Point (Mississippi) | W 39-28 |
| No. 167 Rancho Cucamonga (California) | Norco (California) | W 14-7 |
| No. 168 Picayune (Mississippi) | No. 54 Catholic (Baton Rouge, Louisiana) | L 36-35 OT |
| No. 169 South Pointe (South Carolina) | Gaffney (South Carolina) | L 27-21 |
| No. 170 St. Augustine (Florida) | Idle | |
| No. 171 Timpview (Utah) | No. 117 Los Alamitos (California) | L 57-35 |
| No. 172 Valdosta (Georgia) | Banneker (Georgia) | W 48-7 |
| No. 173 Archbishop Stepinac (New York) | No. 185 Baylor (Tennessee) | L 51-21 |
| No. 174 Liberty (Bakersfield, California) | No. 108 Santa Margarita (California) | L 34-14 |
| No. 175 Houston County (Georgia) | West Laurens (Georgia) | W 55-14 |
| No. 176 Pittsburg (California) | Granite Bay (California) | W 41-21 |
| No. 177 Lake Wales (Florida) | Ridge Community (Florida) | W 40-6 |
| No. 178 Mansfield Timberview (Texas) | White (Dallas, Texas) | W 55-14 |
| No. 179 Bolles School (Florida) | Mandarin (Florida) | L 42-35 |
| No. 180 The Woodlands (Texas) | Lamar (Houston, Texas) | L 45-21 |
| No. 181 Lafayette Christian Academy (Louisiana) | Acadiana (Louisiana) | W 61-38 |
| No. 182 Rabun Gap-Nacoochee (Georgia) | Mays (Georgia) | W 16-6 |
| No. 183 Hamilton (Arizona) | Desert Ridge (Arizona) | W 42-11 |
| No. 184 Miramar (Florida) | Idle | |
| No. 185 Baylor (Tennessee) | No. 173 Archbishop Stepinac (New York) | W 51-21 |
| No. 186 Rockledge (Florida) | No. 6 Duncanville (Texas) | L 44-0 |
| No. 187 Warner Robins (Georgia) | No. 191 Northside (Warner Robins, Georgia) | W 39-35 |
| No. 188 Lone Peak (Utah) | Mountain Ridge (Utah) | L 31-17 |
| No. 189 Palmetto (Miami, Florida) | Lakewood (Florida) | W 26-12 |
| No. 190 Homestead (Florida) | South Dade (Florida) | W 35-0 |
| No. 191 Northside (Warner Robins, Georgia) | No. 187 Warner Robins (Georgia) | L 39-35 |
| No. 192 Clay-Chalkville (Alabama) | Hueytown (Alabama) | W 17-3 |
| No. 193 Parkview (Georgia) | Idle | |
| No. 194 Pearl-Cohn (Tennessee) | Creek Wood (Tennessee) | W 55-8 |
| No. 195 North Gwinnett (Georgia) | Gardendale (Alabama) | W 50-41 |
| No. 196 Douglass (Kentucky) | Idle | |
| No. 197 Lake Mary (Florida) | Idle | |
| No. 198 Norcross (Georgia) | Idle | |
| No. 199 Trinity (Kentucky) | No. 30 Center Grove (Indiana) | L 34-7 |
| No. 200 Teurlings Catholic (Louisiana) | Opelousas (Louisiana) | W 34-16 |
| No. 201 Helix (California) | Red Mountain (Arizona) | W 30-22 |
| No. 202 Christ Presbyterian Academy (Tennessee) | Pope John Paul II (Tennessee) | W 49-20 |
| No. 203 Edison (Huntington Beach, California) | Idle | |
| No. 204 North Crowley (Texas) | Arlington (Texas) | W 69-14 |
| No. 205 St. Rita (Illinois) | Kenwood (Illinois) | W 33-20 |
| No. 206 Bentonville (Arkansas) | No. 252 Conway (Arkansas) | L 42-39 |
| No. 207 Maryville (Tennessee) | Bradley Central (Tennessee) | L 21-13 |
| No. 208 Princeton (Ohio) | Lakota East (Ohio) | L 30-16 |
| No. 209 Madison (San Diego, California) | Oak Ridge (California) | L 22-20 |
| No. 210 De La Salle (Louisiana) | Central (Baton Rouge, Louisiana) | W 27-20 |
| No. 211 Catholic Memorial (Massachusetts) | Regular Season Opens Next Week | |
| No. 212 Red Bank Catholic (New Jersey) | Colts Neck (New Jersey) | W 34-7 |
| No. 213 Highland (Arizona) | No. 28 Basha (Arizona) | W 22-21 |
| No. 214 Monarch (Florida) | Atlantic (Florida) | L 33-32 |
| No. 215 Spartanburg (South Carolina) | Broome (South Carolina) | W 14-13 |
| No. 216 Winton Woods (Ohio) | West Clermont (Ohio) | W 21-13 |
| No. 217 Seton Hall Prep (New Jersey) | Pope John XXIII (New Jersey) | L 33-20 |
| No. 218 Shadow Creek (Texas) | Clear Springs (Texas) | W 20-7 |
| No. 219 Jesuit (Florida) | No. 240 Treasure Coast (Florida) | L 67-28 |
| No. 220 Melissa (Texas) | No. 275 China Spring (Texas) | W 63-33 |
| No. 221 Dutch Fork (South Carolina) | No. 280 Hough (North Carolina) | L 21-17 |
| No. 222 Oak Grove (Mississippi) | No. 120 Hoover (Alabama) | W 28-21 OT |
| No. 223 Cedar Grove (Georgia) | No. 89 Westlake (Atlanta, Georgia) | L 46-41 |
| No. 224 Brandon (Mississippi) | No. 239 Madison Central (Mississippi) | L 40-26 |
| No. 225 Raines (Florida) | Idle | |
| No. 226 Rockwall (Texas) | Dallas Jesuit (Texas) | L 60-59 |
| No. 227 Pickerington Central (Ohio) | No. 257 Centerville (Ohio) | L 28-17 |
| No. 228 Chaminade (California) | No. 92 JSerra (California) | L 41-7 |
| No. 229 Lancaster (Texas) | No. 90 South Oak Cliff (Texas) | L 41-21 |
| No. 230 Lakota West (Ohio) | Fairfield (Ohio) | W 33-0 |
| No. 231 Cathedral Catholic (San Diego, California) | Brophy Prep (Arizona) | L 31-21 |
| No. 232 Bingham (Utah) | No. 95 Skyridge (Utah) | L 35-28 |
| No. 233 Bishop McDevitt (Harrisburg, Pennsylvania) | No. 164 DePaul Catholic (New Jersey) | W 46-42 |
| No. 234 Thomas County Central (Georgia) | Bainbridge (Georgia) | W 45-14 |
| No. 235 Dillard (Florida) | No. 237 Naples (Florida) | L 36-19 |
| No. 236 Davison (Michigan) | Grandville (Michigan) | W 52-21 |
| No. 237 Naples (Florida) | No. 235 Dillard (Florida) | W 36-19 |
| No. 238 Imhotep Charter (Pennsylvania) | Haverford School (Pennsylvania) | 35-0 |
| No. 239 Madison Central (Mississippi) | No. 224 Brandon (Mississippi) | W 40-26 |
| No. 240 Treasure Coast (Florida) | No. 219 Jesuit (Florida) | W 67-28 |
| No. 241 St. Mary’s (Stockton, California) | Manteca (California) | W 44-7 |
| No. 242 Manatee (Florida) | Sarasota (Florida) | W 27-14 |
| No. 243 Mount St. Joseph (Maryland) | Dunbar (Washington, DC) | W 16-6 |
| No. 244 Brentwood (Tennessee) | Hendersonville (Tennessee) | W 43-6 |
| No. 245 Carthage (Texas) | Pittsburg (Texas) | W 42-7 |
| No. 246 Brentwood Academy (Tennessee) | Christian Brothers (Tennessee) | W 37-7 |
| No. 247 Clearwater Central Catholic (Florida) | Trinity Catholic (Florida) | W 35-10 |
| No. 248 Cartersville (Georgia) | Allatoona (Georgia) | W 37-0 |
| No. 249 Tupelo (Mississippi) | Southaven (Mississippi) | W 40-7 |
| No. 250 East Forsyth (North Carolina) | A.C. Reynolds (North Carolina) | W 27-21 |
| No. 251 Lincoln-Way East (Illinois) | Batavia (Illinois) | W 14-13 |
| No. 252 Conway (Arkansas) | No. 206 Bentonville (Arkansas) | W 42-39 |
| No. 253 Westgate (Louisiana) | New Iberia (Louisiana) | W 35-14 |
| No. 254 Byron Nelson (Texas) | McKinney Boyd (Texas) | W 62-3 |
| No. 255 Dublin Coffman (Ohio) | Canton McKinley (Ohio) | L 24-14 |
| No. 256 Warren Easton (Louisiana) | No. 141 Ruston (Louisiana) | W 20-19 |
| No. 257 Centerville (Ohio) | No. 227 Pickerington Central (Ohio) | W 28-17 |
| No. 258 Mason (Ohio) | Hamilton (Ohio) | L 37-6 |
| No. 259 Lake Minneola (Florida) | Vanguard (Florida) | L 35-21 |
| No. 260 Ocean Springs (Mississippi) | Scotlandville (Louisiana) | W 49-0 |
| No. 261 University Lab (Baton Rouge, Louisiana) | Woodlawn (Baton Rouge, Louisiana) | W 40-6 |
| No. 262 De La Salle Collegiate (Michigan) | Muskegon (Michigan) | W 41-28 |
| No. 263 Wayne (Huber Heights, Ohio) | St. Vincent-St. Mary (Ohio) | W 22-11 |
| No. 264 Lovejoy (Texas) | No. 271 Argyle (Texas) | W 42-14 |
| No. 265 St. Charles Catholic (Louisiana) | Archbishop Shaw (Louisiana) | W 17-10 |
| No. 266 State College (Pennsylvania) | Downingtown East (Pennsylvania) | L 28-26 |
| No. 267 Oak Hills (California) | Palmdale (California) | W 65-3 |
| No. 268 Pine-Richland (Pennsylvania) | Kiski Area (Pennsylvania) | W 48-0 |
| No. 269 Carmel (Indiana) | No. 142 Detroit MLK (Michigan) | L 39-0 |
| No. 270 New Bern (North Carolina) | West Craven (North Carolina) | W 43-14 |
| No. 271 Argyle (Texas) | No. 264 Lovejoy (Texas) | L 42-14 |
| No. 272 Westfield (Indiana) | Zionsville (Indiana) | W 28-27 |
| No. 273 Chapman (South Carolina) | Boiling Springs (South Caroilna) | L 29-7 |
| No. 274 Carencro (Louisiana) | Alexandria (Louisiana) | W 46-26 |
| No. 275 China Spring (Texas) | No. 220 Melissa | L 63-33 |
| No. 276 Osceola (Kissimmee, Florida) | No. 113 Seminole (Sanford, Florida) | L 31-6 |
| No. 277 Woodward Academy (Georgia) | Idle | |
| No. 278 Byrnes (South Carolina) | Greenville (South Carolina) | W 37-14 |
| No. 279 Casteel (Arizona) | Queen Creek (Arizona) | W 35-28 |
| No. 280 Hough (North Carolina) | No. 221 Dutch Fork (South Carolina) | W 20-17 |
| No. 281 Pinnacle (Arizona) | Tolleson (Arizona) | W 49-19 |
| No. 282 Gonzaga (Washington, DC) | Calvert Hall (Maryland) | W 24-0 |
| No. 283 Vestavia Hills (Alabama) | Homewood (Alabama) | W 43-0 |
| No. 284 Marist (Georgia) | Savannah Christian (Georgia) | W 21-7 |
| No. 285 Niceville (Florida) | Milton (Florida) | W 42-7 |
| No. 286 Brookwood (Georgia) | Collins Hill (Georgia) | L 31-17 |
| No. 287 American Leadership Academy (Queen Creek, Arizona) | Boulder Creek (Arizona) | W 42-21 |
| No. 288 Sandy Creek (Georgia) | Alexander (Georgia) | W 39-0 |
| No. 289 Harrisburg (Pennsylvania) | Delaware Valley (Pennsylvania) | W 33-0 |
| No. 290 Ensworth (Tennessee) | Trezevant (Tennessee) | W 55-0 |
| No. 291 Prince Avenue Christian (Georgia) | Athens Academy (Georgia) | W 52-21 |
| No. 292 Riverview Sarasota (Florida) | No. 297 Buchholz (Florida) | L 53-31 |
| No. 293 Freedom (Woodbridge, Virginia) | Varina (Virginia) | W 35-27 |
| No. 294 Edmond Santa Fe (Oklahoma) | Choctaw (Oklahoma) | Cancelled |
| No. 295 Jenks (Oklahoma) | Owasso (Oklahoma) | L 34-28 |
| No. 296 Florida State University HS (Florida) | Ponte Vedra (Florida) | L 23-22 |
| No. 297 Buchholz (Florida) | No. 292 Riverview Sarasota (Florida) | W 53-31 |
| No. 298 Corona del Mar (California) | Palos Verdes (California) | L 14-11 |
| No. 299 Rock Creek Christian (Maryland) | No. 8 St. Edward (Ohio) | L 42-14 |
| No. 300 Phoebus (Virginia) | Oscar Smith (Virignia) | W 16-2 |
