It’s another week of 40+ head-to-head matchups inside the High School Football America 300, powered by NFL Play Football. This weekend there are 48 head-to-heads, which means that over the last three weekends 154 head-to-head games have been played.
Saturday Games
In Cincinnati, No. 8 St. Edward surprised a scare with a 34-33 win over No. 122 Elder.
Friday Night Games
In Nevada before a national television audience, No. 3 Bishop Gorman (Nevada) doubled-up No. 20 Corona Centennial (California) 56-28.
High School Football America 300 Scores
| Ranking/Team/State | Ranking/Opponent/State | Score |
| No. 1 St. John Bosco (California) | No. 36 St. Frances Academy (Maryland) | W 37-14 |
| No. 2 Mater Dei (California) | No. 46 Kahuku (Hawaii) | W 55-8 |
| No. 3 Bishop Gorman (Nevada) | No. 20 Corona Centennial (California) | W 56-28 |
| No. 4 IMG Academy (Florida) | No. 109 Ben Davis (Indiana) | W 34-14 |
| No. 5 Buford (Georgia) | Idle | |
| No. 6 Duncanville (Texas) | Idle | |
| No. 7 St. Thomas Aquinas (Florida) | No. 28 Cocoa (Florida) | W 37-36 |
| No. 8 St. Edward (Ohio) | No. 122 Elder (Ohio) | W 34-33 |
| No. 9 Chaminade-Madonna (Florida) | No. 14 Bergen Catholic (New Jersey) | W 61-21 |
| No. 10 Miami Central (Florida) | No. 135 Booker T. Washington (Miami, Florida) | W 38-28 |
| No. 11. St. Joseph’s Prep (Pennsylvania) | No. 92 Lakeland (Florida) | W 45-24 |
| No. 12 Columbus (Miami, Florida) | Jesuit (Tampa, Florida) | W 42-14 |
| No. 13 American Heritage (Plantation, Florida) | Idle | |
| No. 14 Bergen Catholic (New Jersey) | No. 9 Chaminade-Madonna (Florida) | L 61-21 |
| No. 15 Colquitt County (Georgia) | No. 150 Colquitt County (Georgia) | W 37-20 |
| No. 16 Thompson (Alabama) | No. 282 Vestavia Hills (Alabama) | W 21-3 |
| No. 17 North Shore (Texas) | No. 202 Westfield (Texas) | W 45-9 |
| No. 18 DeSoto (Texas) | No. 84 South Oak Cliff (Texas) | W 54-14 |
| No. 19 Mill Creek (Georgia) | Idle | |
| No. 20 Corona Centennial (California) | No. 3 Bishop Gorman (Nevada) | L 56-28 |
| No. 21 Westlake (Austin, Texas) | Akins (Texas) | W 64-0 |
| No. 22 Massillon Washington (Ohio) | Elkhart (Indiana) | W 55-0 |
| No. 23 Walton (Georgia) | Pope (Georgia) | W 67-7 |
| No. 24 Center Grove (Indiana) | No. 277 Archbishop Moeller (Ohio) | W 35-34 OT |
| No. 25 Good Counsel (Maryland) | Idle | |
| No. 26 Archbishop Hoban (Ohio) | East (Akron, Ohio) | W 39-0 |
| No. 27 Orange Lutheran (California) | No. 107 Chandler (Arizona) | L 35-10 |
| No. 28 Cocoa (Florida) | No. 7 St. Thomas Aquinas (Florida) | L 37-36 |
| No. 29 St. John’s College HS (Washington, DC) | Idle | |
| No. 30 DeMatha (Maryland) | No. 291 Freedom (Woodbridge, Virginia) | Cancelled |
| No. 31 Sierra Canyon (California) | Idle | |
| No. 32 Saguaro (Arizona) | No. 72 Basha (Arizona) | L 35-31 |
| No. 33 John Curtis (Louisiana) | Idle | |
| No. 34 Mount Carmel (Chicago, Illinois) | Niles Notre Dame (Illinois) | W 35-0 |
| No. 35 East St. Louis (Illinois) | No. 51 Atascocita (Texas) | L 43-13 |
| No. 36 St. Frances Academy (Maryland) | No. 1 St. John Bosco (California) | L 37-14 |
| No. 37 McCallie (Tennessee) | Memphis University (Tennessee) | W 42-35 |
| No. 38 Lincoln (San Diego, California) | Mater Dei Catholic (California) | W 54-19 |
| No. 39 Central (Phenix City, Alabama) | No. 125 Enterprise (Alabama) | W 48-7 |
| No. 40 Southlake Carroll (Texas) | No. 298 Cedar Hill (Texas) | W 31-6 |
| No. 41 Saraland (Alabama) | St. Paul’s Episcopal (Alabama) | W 47-3 |
| No. 42 Aledo (Texas) | Northwest (Texas) | W 38-13 |
| No. 43 Liberty (Arizona) | Queen Creek (Arizona) | W 56-0 |
| No. 44 Denton Guyer (Texas) | No. 241 Lancaster (Texas) | W 28-20 |
| No. 45 Lipscomb Academy (Tennessee) | No. 177 Baylor (Tennessee) | L 34-31 |
| No. 46 Kahuku (Hawaii) | No. 2 Mater Dei (California) | L 55-8 |
| No. 47 Catholic (Baton Rouge, Louisiana) | No. 197 Warren Easton (Louisiana) | L 49-26 |
| No. 48 Langston Hughes (Georgia) | Idle | |
| No. 49 Carrollton (Georgia) | Villa Rica (Georgia) | W 50-0 |
| No. 50 Serra (San Mateo, California) | Modesto Central Catholic (California) | W 38-7 |
| No. 51 Atascocita (Texas) | No. 35 East St. Louis (Illinois) | W 43-13 |
| No. 52 Cardinal Gibbons (Florida) | No. 224 Dillard (Florida) | W 38-14 |
| No. 53 Edgewater (Florida) | West Orange (Florida) | W 27-13 |
| No. 54 Edna Karr (Louisiana) | Scotlandville (Louisiana) | W 45-0 |
| No. 55 Long Beach Poly (California) | No. 136 Serra (Gardena, California) | W 28-24 |
| No. 56 St. Xavier (Kentucky) | Idle | |
| No. 57 Mission Viejo (California) | Highland (California) | W 58-0 |
| No. 58 Toledo Central Catholic (Ohio) | Brother Rice (Michigan) | W 33-7 |
| No. 59 Jones (Orlando, Florida) | Osceola (Kissimmee, Florida) | W 28-20 |
| No. 60 Belleville (Michigan) | Churchill (Michigan) | W 56-0 |
| No. 61 Bartram Trail (Florida) | No. 137 Mainland (Florida) | L 28-24 |
| No. 62 Katy (Texas) | Katy Tompkins (Texas) | W 41-7 |
| No. 63 Corner Canyon (Utah) | Syracuse (Utah) | W 42-14 |
| No. 64 Archbishop Spalding (Maryland) | No. 213 Imhotep Charter (Pennsylvania) | L 21-17 |
| No. 65 Norland (Florida) | Southridge (Florida) | W 54-6 |
| No. 66 Gainesville (Georgia) | Clarke Central (Georgia) | W 24-7 |
| No. 67 Oakland (Tennessee) | Antioch (Tennessee) | W 49-0 |
| No. 68 Vandegrift (Texas) | Midway (Texas) | W 48-17 |
| No. 69 Armwood (Florida) | Hillsborough (Florida) | W 48-12 |
| No. 70 Highland Springs (Virginia) | Maury (Virginia) | L 23-14 |
| No. 71 Highland (Arizona) | Lone Peak (Utah) | W 35-24 |
| No. 72 Basha (Arizona) | No. 32 Saguaro (Arizona) | L 35-31 |
| No. 73 Clearwater Academy International (Florida) | Benjamin (Florida) | L 27-21 |
| No. 74 Brownsburg (Indiana) | Avon (Indiana) | W 53-30 |
| No. 75 Loyola Academy (Illinois) | Marist (Illinois) | W 34-7 |
| No. 76 Roswell (Georgia) | No. 145 Milton (Georgia) | L 34-14 |
| No. 77 Destrehan (Louisiana) | John Ehret (Louisiana) | W 24-7 |
| No. 78 Trinity Christian Academy (Jacksonville, Florida) | North Florida Educational Institute (Florida) | W 43-0 |
| No. 79 Brother Martin (Louisiana) | St. Paul’s (Louisiana) | W 23-10 |
| No. 80 Vero Beach (Florida) | Palm Beach Gardens (Florida) | W 26-11 |
| No. 81 Westlake (Atlanta, Georgia) | Southwest DeKalb (Georgia) | W 57-7 |
| No. 82 St. Xavier (Ohio) | Withrow (Ohio) | W 14-10 |
| No. 83 Venice (Florida) | No. 85 Northwestern (Miami, Florida) | W 63-46 |
| No. 84 South Oak Cliff (Texas) | No. 18 DeSoto (Texas) | L 54-14 |
| No. 85 Northwestern (Miami, Florida) | No. 83 Venice (Florida) | L 63-46 |
| No. 86 Folsom (California) | Turlock (California) | W 49-7 |
| No. 87 Bixby (Oklahoma) | Charles Page (Oklahoma) | W 61-7 |
| No. 88 Male (Kentucky) | Idle | |
| No. 89 Prosper (Texas) | No. 296 Rockwall (Texas) | L 47-41 |
| No. 90 Bryant (Arkansas) | Parkview (Arkansas) | L 28-27 |
| No. 91 JSerra (California) | Notre Dame (Sherman Oaks, Caifornia) | W 34-14 |
| No. 92 Lakeland (Florida) | No. 11 St. Joseph’s Prep (Pennsylvania) | L 45-24 |
| No. 93 Lake Travis (Texas) | Johnson (Buda, Texas) | W 52-24 |
| No. 94 Skyridge (Utah) | Riverton (Utah) | W 58-10 |
| No. 95 Providence Day (North Carolina) | Cannon (North Carolina) | W 49-7 |
| No. 96 Santa Margarita (California) | Bishop Amat (California) | W 51-45 |
| No. 97 Alcoa (Tennessee) | Greenville (Tennessee) | Cancelled |
| No. 98 Union (Oklahoma) | Jenks (Oklahoma) | L 31-24 |
| No. 99 Carlsbad (California) | No. 271 Casteel (Arizona) | W 49-9 |
| No. 100 Cathedral (Indiana) | Bishop Chatard (Indiana) | L 24-21 |
| No. 101 Don Bosco Prep (New Jersey) | No. 103 St. Joseph Regional (Montvale, New Jersey) | Sunday |
| No. 102 Grimsley (North Carolina) | Idle | |
| No. 103 St. Joseph Regional (Montvale, New Jersey) | No. 101 Don Bosco Prep (New Jersey) | Sunday |
| No. 104 Christian Brothers College (Missouri) | St. Louis University (Missouri) | W 49-14 |
| No. 105 West (Knoxville, Tennessee) | Maryville (Tennessee) | W 21-14 |
| No. 106 Lehi (Utah) | Herriman (Utah) | W 48-28 |
| No. 107 Chandler (Arizona) | No. 27 Orange Lutheran (California) | W 35-10 |
| No. 108 Mallard Creek (North Carolina) | No. 211 Gaffney (South Carolina) | L 24-7 |
| No. 109 Ben Davis (Indiana) | No. 4 IMG Academy (Florida) | L 34-14 |
| No. 110 Butler (North Carolina) | No. 128 Weddington (North Carolina) | W 22-15 |
| No. 111 Seminole (Sanford, Florida) | No. 214 Treasure Coast (Florida) | L 14-9 |
| No. 112 Los Alamitos (California) | Servite (California) | L 28-24 |
| No. 113 Hewitt-Trussville (Alabama) | Oak Mountain (Alabama) | W 42-7 |
| No. 114 Cherry Creek (Colorado) | Chatfield (Colorado) | W 34-17 |
| No. 115 Hamilton Southeastern (Indiana) | Fishers (Indiana) | W 35-34 |
| No. 116 St. Thomas More (Louisiana) | Alexandria (Louisiana) | W 49-21 |
| No. 117 South Florence (South Carolina) | Carolina Forest (South Carolina) | W 30-22 |
| No. 118 Apopka (Florida) | Dr. Phillips (Florida) | W 18-14 |
| No. 119 Northwestern (South Carolina) | Nation Ford (South Carolina) | W 62-0 |
| No. 120 Pickerington North (Ohio) | No. 239 Pickerington Central (Ohio) | W 39-27 |
| No. 121 Grayson (Georgia) | No. 215 Spartanburg (South Carolina) | W 21-19 |
| No. 122 Elder (Ohio) | No. 8 St. Edward (Ohio) | L 34-33 |
| No. 123 Benedictine (Georgia) | No. 134 Ware County (Georgia) | W 34-24 |
| No. 124 Iona Prep (New York) | Chaminade (New York) | W 31-7 |
| No. 125 Enterprise (Alabama) | No. 41 Central (Phenix City, Alabama) | L 48-7 |
| No. 126 Auburn (Alabama) | Dothan (Alabama) | W 28-27 2OT |
| No. 127 Oaks Christian (California) | Idle | |
| No. 128 Weddington (North Carolina) | No. 110 Butler (North Carolina) | L 22-15 |
| No. 129 Cibolo Steele (Texas) | Hutto (Texas) | W 57-27 |
| No. 130 Rome (Georgia) | Pebblebrook (Georgia) | W 48-7 |
| No. 131 Oak Grove (Mississippi) | Hattiesburg (Mississippi) | W 32-14 |
| No. 132 Creekside (Georgia) | Idle | |
| No. 133 Hoover (Alabama) | Spain Park (Alabama) | W 28-20 |
| No. 134 Ware County (Georgia) | No. 123 Benedictine (Georgia) | L 31-24 |
| No. 135 Booker T. Washington (Miami, Florida) | No. 10 Miami Central (Florida) | L 38-28 |
| No. 136 Serra (Gardena, California) | No. 55 Long Beach Poly (California) | L 28-24 |
| No. 137 Mainland (Florida) | No. 61 Bartram Trail (Florida) | W 28-24 |
| No. 138 DuPont Manual (Kentucky) | Eastern (Kentucky) | W 43-0 |
| No. 139 De La Salle (California) | St. Francis (Mountain View, California) | W 35-17 |
| No. 140 Lincoln (Gahanna, Ohio) | Reynoldsburg (Ohio) | W 49-6 |
| No. 141 Highland Park (Texas) | Lake Highlands (Texas) | L 30-13 |
| No. 142 Lewisville (Texas) | Mesquite (Texas) | W 36-0 |
| No. 143 Western (Davie, Florida) | Coconut Creek (Florida) | L 20-15 |
| No. 144 Inglewood (California) | Gonzaga Prep (Washington) | W 32-19 |
| No. 145 Milton (Georgia) | No. 76 Roswell (Georgia) | W 34-14 |
| No. 146 Pulaski Academy (Arkansas) | Russellville (Arkansas) | W 48-10 |
| No. 147 Liberty (Nevada) | Coronado (Nevada) | W 49-7 |
| No. 148 Tampa Bay Tech (Florida) | Newsome (Florida) | W 43-7 |
| No. 149 Kings (Ohio) | Loveland (Ohio) | L 31-20 |
| No. 150 Lee County (Georgia) | No. 15 Colquitt County (Georgia) | L 37-20 |
| No. 151 St. Augustine (Louisiana) | Landry-Walker (Louisiana) | W 40-0 |
| No. 152 McKinney (Texas) | Flower Mound (Texas) | W 30-7 |
| No. 153 Zachary (Louisiana) | Idle | |
| No. 154 Longview (Texas) | Tyler Legacy (Texas) | W 28-7 |
| No. 155 Dripping Springs (Texas) | Idle | |
| No. 156 Bishop McDevitt (Harrisburg, Pennsylvania) | LaSalle College HS (Pennsylvania) | W 47-21 |
| No. 157 American Fork (Utah) | No. 244 Bingham (Utah) | W 28-0 |
| No. 158 Starkville (Mississippi) | Meridian (Mississippi) | W 42-21 |
| No. 159 Rancho Cucamonga (California) | Valencia (California) | W 22-20 |
| No. 160 Warner Robins (Georgia) | No. 167 Valdosta (Georgia) | L 49-12 |
| No. 161 Pittsburgh Central Catholic (Pennsylvania) | Bethel Park (Pennsylvania) | W 62-46 |
| No. 162 Picayune (Mississippi) | D’iberville (Mississippi) | W 42-0 |
| No. 163 DePaul Catholic (New Jersey) | No. 189 St. Peter’s Prep (New Jersey) | W 46-20 |
| No. 164 Lake Wales (Florida) | Sebring (Florida) | W 7-0 |
| No. 165 Houston County (Georgia) | Locust Grove (Georgia) | W 56-12 |
| No. 166 Pittsburg (California) | Monterey Trail (California) | W 10-7 |
| No. 167 Valdosta (Georgia) | No. 160 Warner Robins (Georgia) | W 49-12 |
| No. 168 Avon (Ohio) | Elyria (Ohio) | W 42-6 |
| No. 169 North Cobb (Georgia) | Marietta (Georgia) | W 32-22 |
| No. 170 Glenville (Ohio) | John Adams (Ohio) | W 38-0 |
| No. 171 St. Augustine (Florida) | Brunswick (Georgia) | W 45-35 |
| No. 172 Timpview (Utah) | Springville (Utah) | W 17-0 |
| No. 173 Mansfield Timberview (Texas) | White (Dallas, Texas) | W 27-7 |
| 174 Palmetto (Miami, Florida) | Killian (Florida) | W 38-0 |
| No. 175 Rabun Gap-Nacoochee (Georgia) | Christ School (North Carolina) | W 42-21 |
| No. 176 Homestead (Florida) | Lakewood (Florida) | W 35-7 |
| No. 177 Baylor (Tennessee) | No. 45 Lipscomb Academy (Tennessee) | W 34-31 |
| No. 178 Lafayette Christian Academy (Louisiana) | Woodlawn (Baton Rouge, Louisiana) | W 42-14 |
| No 179 Miramar (Florida) | Coral Glades (Florida) | W 61-0 |
| No. 180 Hamilton (Arizona) | Boulder Creek (Arizona) | W 59-15 |
| No. 181 Archbishop Stepinac (New York) | Monsignor Farrell (New York) | W 21-16 |
| No. 182 Clay-Chalkville (Alabama) | Pell City (Alabama) | W 47-7 |
| No. 183 Parkview (Georgia) | No. 186 North Gwinnett (Georgia) | W 35-32 |
| No. 184 Helix (California) | No. 221 Madison (San Diego, California) | W 53-19 |
| No. 185 Pearl-Cohn (Tennessee) | PURE Academy (Tennessee) | W 41-14 |
| No. 186 North Gwinnett (Georgia) | No. 183 Parkview (Georgia) | L 35-32 |
| No. 187 Liberty (Bakersfield, California) | Buchanan (Clovis, California) | W 35-30 |
| No. 188 Northside (Warner Robins, Georgia) | Idle | |
| No. 189 St. Peter’s Prep (New Jersey) | No. 163 DePaul Catholic (New Jersey) | L 46-20 |
| No. 190 Teurlings Catholic (Louisiana) | Avoyelles (Louisiana) | W 45-14 |
| No. 191 Christ Presbyterian Academy (Tennessee) | Montgomery Bell Academy (Tennessee) | W 22-7 |
| No. 192 St. Rita (Illinois) | Joliet Catholic (Illinois) | W 20-10 |
| No. 193 Edison (Huntington Beach, California) | Palos Verdes (Califoria) | L 31-28 |
| No. 194 North Crowley (Texas) | No. 256 Lovejoy (Texas) | W 43-20 |
| No. 195 Princeton (Ohio) | Mason (Ohio) | W 20-3 |
| No. 196 Fort Bend Hightower (Missouri, Texas) | Fort Bend Travis (Texas) | W 40-10 |
| No. 197 Warren Easton (Louisiana) | No. 47 Catholic (Baton Rouge, Louisiana) | W 49-26 |
| No. 198 Ruston (Louisiana) | Jesuit (Louisiana) | W 35-7 |
| No. 199 Douglass (Kentucky) | Tates Creek (Kentucky) | W 43-0 |
| No. 200 Lake Mary (Florida) | Oviedo (Florida) | W 46-17 |
| No. 201 Norcross (Georgia) | Archer (Georgia) | W 25-21 |
| No. 202 Westfield (Texas) | No. 17 North Shore (Texas) | L 45-9 |
| No. 203 Red Bank Catholic (New Jersey) | Idle | |
| No. 204 Winton Woods (Ohio) | Turpin (Ohio) | W 20-0 |
| No. 205 De La Salle (Louisiana) | Holy Cross (Louisiana) | L 49-27 |
| No. 206 Trotwood-Madison (Ohio) | Archbishop Alter (Ohio) | W 35-27 |
| No. 207 Springfield (Ohio) | No. 255 Wayne (Huber Heights, Ohio) | L 27-22 |
| No. 208 Conway (Arkansas) | Springdale (Arkansas) | W 49-0 |
| No. 209 Crest (North Carolina) | Idle | |
| No. 210 Bentonville (Arkansas) | Idle | |
| No. 211 Gaffney (South Carolina) | No. 108 Mallard Creek (North Carolina) | W 24-7 |
| No. 212 South Pointe (South Carolina) | Chester (South Carolina) | W 31-0 |
| No. 213 Imhotep Charter (Pennsylvania) | No. 64 Archbishop Spalding (Maryland) | W 21-17 |
| No. 214 Treasure Coast (Florida) | No. 111 Seminole (Sanford, Florida) | W 14-9 |
| No. 215 Spartanburg (South Carolina) | No. 121 Grayson (Georgia) | L 21-19 |
| No. 216 Catholic Memorial (Massachusetts) | Mansfield (Massachusetts | W 41-14 |
| No. 217 Fort Dorchester (South Carolina) | Idle | |
| No. 218 Naples (Florida) | Immokalee (Florida) | W 33-17 |
| No. 219 Lincoln-Way East (Illinois) | Neuqua Valley (Illinois) | W 35-7 |
| No. 220 Oak Ridge (California) | Clayton Valley Charter (California) | W 27-0 |
| No. 221 Madison (San Diego, California) | No. 184 Helix (California) | L 53-19 |
| No. 222 Madison Central (Mississippi) | Gulfport (Mississippi) | W 23-21 |
| No. 223 Melissa (Texas) | Royse City (Texas) | W 39-7 |
| No. 224 Dillard (Florida) | No. 52 Cardinal Gibbons (Florida) | L 38-14 |
| No. 225 Davison (Michigan) | Traverse City Central (Michigan) | W 49-7 |
| No. 226 St. Mary’s (Stockton, California) | Idle | |
| No. 227 Manatee (Florida) | Charlotte (Florida) | W 46-7 |
| No. 228 Mount St. Joseph (Maryland) | St. Mary’s Ryken (Maryland) | Monday |
| No. 229 Shadow Creek (Texas) | Bridgeland (Texas) | W 41-24 |
| No. 230 Atlantic (Delray Beach, Florida) | North Miami Beach (Florida) | W 36-13 |
| No. 231 Monarch (Florida) | Hallandale (Florida) | W 52-0 |
| No. 232 Cedar Grove (Georgia) | Collins Hill (Georgia) | W 37-26 |
| No. 233 Raines (Florida) | Sandalwood (Florida) | W 26-7 |
| No. 234 Centerville (Ohio) | Miamisburg (Ohio) | W 27-14 |
| No. 235 Thomas County Central (Georgia) | Idle | |
| No. 236 Buchholz (Florida) | Eastside (Gainesville, Florida) | W 35-0 |
| No. 237 St. Ignatius (Ohio) | Austintown-Fitch (Ohio) | L 24-21 |
| No. 238 Brentwood (Tennessee) | Henry Academy (Tennessee) | W 17-14 |
| No. 239 Pickerington Central (Ohio) | No. 120 Pickerington North (Ohio) | L 39-27 |
| No. 240 Chaminade (California) | Cathedral (California) | W 31-14 |
| No. 241 Lancaster (Texas) | No. 44 Denton Guyer (Texas) | L 28-20 |
| No. 242 Lakota West (Ohio) | Middletown (Ohio) | W 35-0 |
| No. 243 Carthage (Texas) | Cornerstone Christian (San Antonio, Texas) | W 34-0 |
| No. 244 Bingham (Utah) | No. 157 American Fork (Utah) | L 28-0 |
| No. 245 Brentwood Academy (Tennessee) | Father Ryan (Tennessee) | L 56-21 |
| No. 246 Clearwater Central Catholic (Florida) | Tampa Catholic (Florida) | W 37-10 |
| No. 247 Cartersville (Georgia) | Columbia (Georgia) | W 31-6 |
| No. 248 Tupelo (Mississippi) | Hernando (Mississippi) | W 40-0 |
| No. 249 East Forsyth (North Carolina) | Idle | |
| No. 250 Westgate (Louisiana) | Lake Charles College Prep (Louisiana) | W 43-7 |
| No. 251 Byron Nelson (Texas) | Braswell (Texas) | W 31-10 |
| No. 252 Ocean Springs (Mississippi) | Northwest Rankin (Mississippi) | W 27-24 |
| No. 253 University Lab (Baton Rouge, Louisiana) | Archbishop Rummel (Louisiana) | L 20-17 |
| No. 254 De La Salle Collegiate (Michigan) | St. Mary’s Prep (Michigan) | W 41-27 |
| No. 255 Wayne (Huber Heights, Ohio) | No. 207 Sprinfield (Ohio) | W 27-22 |
| No. 256 Lovejoy (Texas) | No. 194 North Crowley (Texas) | L 43-20 |
| No. 257 St. Charles Catholic (Louisiana) | Lutcher (Louisiana) | W 16-14 |
| No. 258 Oak Hills (California) | Citrus Valley (California | W 24-19 |
| No. 259 Pine-Richland (Pennsylvania) | Penn Hills (Pennsylvania) | L 26-20 |
| No. 260 Carmel (Indiana) | No. 266 Trinity (Kentucky) | L 41-14 |
| No. 261 New Bern (North Carolina) | Knightdale (North Carolina) | W 49-0 |
| No. 262 Dublin Coffman (Ohio) | Dublin Jerome (Ohio) | W 35-14 |
| No. 263 Brandon (Mississippi) | Clinton (Mississippi) | W 31-10 |
| No. 264 East Central (Indiana) | Franklin County (Indiana) | W 55-0 |
| No. 265 Mandarin (Florida) | Riverside (Jacksonville, Florida) | W 50-20 |
| No. 266 Trinity (Kentucky) | No. 260 Carmel (Indiana) | W 41-14 |
| No. 267 Bolles School (Florida) | Coffee (Georgia) | L 17-9 |
| No. 268 Rockledge (Florida) | Viera (Florida) | W 59-21 |
| No. 269 Westfield (Indiana) | Idle | |
| No. 270 Woodward Academy (Georgia) | No. 283 Marist (Georgia) | L 17-10 OT |
| No. 271 Casteel (Arizona) | No. 99 Carlsbad (California) | L 49-9 |
| No. 272 C.E. King (Texas) | Pearland (Texas) | W 40-29 |
| No. 273 Carencro (Louisiana) | Barbe (Louisiana) | W 60-14 |
| No. 274 Byrnes (South Carolina) | Greer (South Carolina) | W 49-13 |
| No. 275 Hough (North Carolina) | Idle | |
| No. 276 Dutch Fork (South Carolina) | Stratford (South Carolina) | W 54-7 |
| No. 277 Archbishop Moeller (Ohio) | No. 24 Center Grove (Indiana) | L 35-34 OT |
| No. 278 Delbarton (New Jersey) | Malvern Prep (Pennsylvania) | L 20-17 |
| No. 279 Gonzaga (Washington, DC) | Fordham Prep (New York) | W 45-0 |
| No. 280 Pope John XXIII (New Jersey) | Paramus Catholic (New Jersey) | W 47-40 |
| No. 281 Pinnacle (Arizona) | Corona del Sol (Arizona) | W 57-27 |
| No. 282 Vestavia Hills (Alabama) | No. 16 Thompson (Alabama) | L 21-3 |
| No. 283 Marist (Georgia) | No. 270 Woodward Academy (Georgia) | W 17-10 OT |
| No. 284 Niceville (Florida) | Lincoln (Tallahassee, Florida) | L 28-14 |
| No. 285 American Leadership Academy (Queen Creek, Arizona) | American Leadership Academy – Gilberty N (Arizona) | W 49-28 |
| No. 286 Sandy Creek (Georgia) | East Coweta (Georgia) | L 31-14 |
| No. 287 Argyle (Texas) | Grapevine (Texas) | W 7-0 |
| No. 288 Harrisburg (Pennsylvania) | Manheim Township (Pennsylvania) | L 38-6 |
| No. 289 Ensworth (Tennessee) | Knoxville Catholic (Tennessee) | W 38-14 |
| No. 290 Prince Avenue Christian (Georgia) | Monroe Area (Georgia) | W 76-20 |
| No. 291 Freedom (Woodbridge, Virginia) | No. 30 DeMatha (Maryland) | Cancelled |
| No. 292 St. Anthony’s (Melville, New York) | Cardinal Hayes (New York | W 52-51 |
| No. 293 Phoebus (Virginia) | Woodside (Virginia) | W 34-0 |
| No. 294 China Spring (Texas) | Mexia (Texas) | W 69-27 |
| No. 295 Edmond Santa Fe (Oklahoma) | Norman North (Oklahoma) | L 31-28 |
| No. 296 Rockwall (Texas) | No. 89 Prosper | W 47-41 |
| No. 297 Lowndes (Georgia) | Rock Creek Christian Academy (Maryland) | W 23-12 |
| No. 298 Cedar Hill (Texas) | No. 40 Southlake Carroll (Texas) | L 31-6 |
| No. 299 Vanguard (Florida) | Dunnellon (Florida) | W 28-21 |
| No. 300 Punahou (Hawaii) | Idle |
