The South Carolina High School League has set the regions for all five classifications for the 2024 and 2025 high school football seasons. Below is the alignment through the 2025 football season.
5A
Region 1
- Easley
- Greenville
- Greenwood
- Hillcrest
- J.L. Mann
- Mauldin
- T.L. Hanna
- Woodmont
Region 2
- Boiling Springs
- Dorman
- Eastside
- Gaffney
- Byrnes
- Riverside
- Spartanburg
- Wade Hampton
Region 3
- Catawba Ridge
- Clover
- Fort Mill
- Indian Land
- Nation Ford
- Northwestern
- Rock Hill
Region 4
- Chapin
- Dutch Fork
- Irmo
- Lexington
- River Bluff
- White Knoll
Region 5
- Blythewood
- Lugoff-Elgin
- Ridge View
- Spring Valley
- Sumter
- Westwood
- West Florence
Region 6
- Carolina Forest
- Conway
- Myrtle Beach
- North Myrtle Beach
- Socastee
- St. James
Region 7
- Berkeley
- Cane Bay
- Goose Creek
- Lucy Beckham
- Stratford
- Wando
Region 8
- Ashley Ridge
- Fort Dorchester
- James Island
- R.B. Stall
- Summerville
- West Ashley
4A
Region 1
- Emerald
- Fountain Inn
- Laurens
- Southside
- Westside
- Wren
Region 2
- Berea
- Blue Ridge
- Daniel
- Greer
- Pickens
- Seneca
- Travelers Rest
Region 3
- A.C. Flora
- Camden
- Dreher
- Lancaster
- Richland Northeast
- South Pointe
- York
Region 4
- Aiken
- Airport
- Brookland-Cayce
- Gilbert
- Gray Collegiate
- Midland Valley
- North Augusta
- South Aiken
Region 5
- Crestwood
- Darlington
- Hartsville
- Lakewood
- Lower Richland
- South Florence
- Wilson
Region 6
- Beaufort
- Bishop England
- Bluffton
- Colleton County
- Hilton Head Island
- May River
3A
Region 1
- Belton-Honea Path
- Crescent
- Pendleton
- Walhalla
- West-Oak
Region 2
- Carolina
- Christ Church
- Palmetto
- Powdersville
- Southside Christian
- St. Joseph’s
Region 3
- Broome
- Chapman
- Mountain View
- Union County
- Woodruff
Region 4
- Fox Creek
- Keenan
- Newberry
- Silver Bluff
- Swansea
Region 5
- Aynor
- Dillon
- Georgetown
- Loris
- Marlboro County
- Waccamaw
Region 6
- Battery Creek
- Hanahan
- North Charleston
- Oceanside Collegiate
- Orangeburg-Wilkinson
2A
Region 1
- Blacksburg
- Chesnee
- Landrum
- Liberty
- Clinton
Region 2
- American Leadership
- Batesburg-Leesville
- Ninety Six
- Pelion
- Saluda
- Strom Thurmond
Region 3
- Chester
- Clinton
- Columbia
- Eau Claire
- Fairfield Central
- Mid-Carolina
Region 4
- Andrew Jackson
- Buford
- Central
- Cheraw
- Chesterfield
- North Central
Regtion 5
- Barnwell
- Edisto
- Hampton County
- Lake Marion
- Whale Branch
Region 6
- Academic Magnet
- Andrew
- Burke
- Philip Simmons
- Timberland
- Woodland
Region 7
- Atlantic Collegiate
- East Clarendon
- Kingstree
- Lake City
- Manning
- Marion
- Mullins
1A
Region 1
- Abbeville
- Calhoun Falls
- Dixie
- McCormick
- Thonwell
- Ware Shoals
Region 2
- C.A. Johnson
- Great Falls
- Lamar
- Lee Central
- Lewisville
- McBee
Region 3
- Blackville-Hilda
- Calhoun County
- Hunter-Kinard-Tyler
- North
- Ridge Spring-Monetta
- Wagener-Salley
- Williston-Elko
Region 4
- Allendale-Fairfax
- Bamberg-Ehrhardt
- Denmark-Olar
- Hardeeville
- Ridgeland
Region 5
- Baptist Hill
- Bethune-Bowman
- Branchville
- Cross
- Military Magnet
- Scott’s Branch
- St. John’s
Region 6
- Carvers Bay
- Green Sea Floyds
- Hannah Pamplico
- Hemingway
- Johnsonville
- Lake View
- Latta
