For the second time in the last three NFL Drafts, Texas is the leader in former high school football players selected. 32 former high schoolers from the Lone Star State were chosen during the three-day event held in Las Vegas, Nevada.
Klein Collins led the way with two former players chosen.
Former running back Isaiah Spiller was taken with the 123rd pick by the Los Angeles Chargers. With the 224 pick, the Miami Dolphins chose linebacker Cameron Goode.
The top pick from Texas was former Lake Travis wide receiver Garrett Wilson. He was taken 10th overall by the New York Jets.
Falling-in behind Texas with the most picks was Georgia with 30, California with 22 and Florida with 21.
2022 NFL Draft – Texas Picks
| Pick | Team | Player | Position | High School |
| No. 10 | New York Jets | Garrett Wilson | WR | Lake Travis |
| No. 15 | Houston Texans | Kenyon Green | G | Atascocita |
| No. 24 | Dallas Cowboys | Tyler Smith | OT | North Crowley |
| No. 32 | Minnesota Vikings | Lewis Cine | S | Cedar Hill Trinity Christian |
| No. 33 | Tampa Bay Buccaneers | Logan Hall | DE | Belton |
| No. 37 | Houston Texans | Jalen Pitre | S | Stafford |
| No. 59 | Minnesota Vikings | Ed Ingram | OG | DeSoto |
| No. 79 | Los Angeles Chargers | JT Woods | S | Cibolo Steele |
| No. 84 | Pittsburgh Steelers | DeMarvin Leal | DE | Judson |
| No. 89 | Buffalo Bills | Terrel Bernard | ILB | La Porte |
| No. 105 | San Francisco 49ers | Danny Gray | WR | Dallas James Madison |
| No. 117 | New York Jets | Micheal Clemons | DE | Sachse |
| No. 118 | Minnesota Vikings | Akayleb Evans | CB | McKinney |
| No. 123 | Los Angeles Chargers | Isaiah Spiller | RB | Klein Collins |
| No. 124 | Cleveland Browns | Cade York | PK | Prosper |
| No. 125 | Miami Dolphins | Erik Ezukanma | WR | Timber Creek |
| No. 134 | San Francisco 49ers | Spencer Burford | OT | San Antonio Wagner |
| No. 137 | New England Patriots | Bailey Zappe | QB | Victoria East |
| No. 152 | Denver Broncos | Delarrin Turner-Yell | S | Hempstead |
| No. 153 | Seattle Seahawks | Tariq Woolen | CB | Arlington Heights |
| No. 157 | Tampa Bay Buccaneers | Zyon McCollum | CB | Ball |
| No. 160 | Los Angeles Chargers | Otito Ogonnia | DT | Katy Taylor |
| No. 181 | Philadelphia Eagles | Kyron Johnson | ILB | Arlington Lamar |
| No. 201 | Arizona Cardinals | Keaontay Ingram | RB | Carthage |
| No. 202 | Cleveland Browns | Michael Woods II | WR | Magnolia |
| No. 203 | Chicago Bears | Trestan Ebner | RB | Henderson |
| No. 205 | Houston Texans | Austin Deculus | OT | Cy-Fair |
| No. 210 | New England Patriots | Chasen Hines | G | Marshall |
| No. 224 | Miami Dolphins | Cameron Goode | OLB | Klein Collins |
| No. 230 | Washington Commanders | Chris Paul | G | Jersey Village |
| No. 242 | Carolina Panthers | Kalon Barnes | CB | Silsbee |
| No. 246 | Cleveland Browns | Dawson Deaton | CB | Frisco |
