It’s the first weekend in October with plenty of big head-to-head matchups inside the High School Football America 300 national rankings, powered by NFL Play Football.
This weekend’s biggest games will be in Southern California with the opening of Trinity League play. All six teams in the league are ranked between No. 1 and No. 46.
Four-time HSFA national champ Mater Dei controls its own destiny when it comes to winning back-to-back national crowns.
Related: Trinity League Week 1 Recap
Saturday Games
In Pennsylvania, No. 129 La Salle College High School won a four overtime nail biter against No. 27 St. Joseph’s Prep 35-34.
With an estimated crowd of 15,000 fans watching, the Explorers improved to 6-0 with the win over the two-time reigning 6A champs. The game was tied at 14-14 in regulation.
La Salle beat SJP for the first time since 2021 by going for two in the fourth OT. The Explorers tried to execute a “Philly Special-type” play, but the Hawks shut it down, which led to wide receiver Joey O’Brien tossing the winning score to Desmond Ortiz.
Below, you can watch the entire game that was produced by the SJP students.
In Georgia, No. 147 Valdosta beat No. 134 Camden County 56-37 in a battle of unbeatens in 6A Region 1.
In Hawaii, No. 42 Mililani was handed its first loss by Campbell. Saber quarterback Jaron-Keawe Sagapolutel, Cal-recruit, tossed six touchdown passes in the win.
Friday Games
In Southern California, No. 2 St. John Bosco had to overcome a 10-0 halftime deficit against No. 12 Orange Lutheran. In a back-and-forth second half, Bosco won 28-24.
Bosco had to start freshman Koa Malau’ulu at quarterback with regular starter Matai Fuiava, who was injured. Malau’ulu tossed four second half touchdowns in the win.
In Florida, No. 14 Venice gave No. 7 IMG Academy all it could handle in a 21-16 loss. The Ascender defense never gave up the lead against a Venice offense averaging over 55 points a game.
In Alabama, No. 219 Auburn beat No. 28 Central (Phenix City) 38-33.
In Texas, No. 34 Atascocita edged No. 52 Summer Creek 42-39 in a wild game.
Atascocita took at 35-7 lead, but Summer Creek battled back to take a 39-35 lead with just over three minutes to play. That’s when the Eagles put together a 72 yard drive that ended with Tory Blaylock scoring from a yard out with just :12 seconds to play.
There were two big HSFA 300 head-to-heads in Arizona.
No. 67 Liberty beat No. 77 Chandler 45-20. Liberty, the reigning Open Division champs, are now 4-1. Chandler, losers of two straight, is now 4-2.
No. 75 Basha handed No. 165 Brophy Prep its first loss of the season. The Bears won 35-32 behind a couple of rushing touchdowns by sophomore Noah Roberts.
Thursday Games
In Arizona, unranked Red Mountain surprised No. 62 Highland in a battle of unbeatens. The Mountain Lions beat the Hawks 28-11 to improve to 6-0. Look for Lions to move into the national rankings when the new Top 300 is released on Sunday.
In Florida, No. 100 Armwood is now after shutting out Plant 26-0.
In Alabama, No. 256 Enterprise edged No. 283 Carver Montgomery 17-14 in a big 7A Region 2 game at the legendary Cramton Bowl.
High School Football America 300 Scores
| Ranking/Team/State | Opponent | Result |
| No. 1 Mater Dei (California) | No. 41 Santa Margarita (California) | W 40-18 |
| No. 2 St. John Bosco (California) | No. 12 Orange Lutheran (California) | W 28-24 |
| No. 3 Bishop Gorman (Nevada) | Foothill (Nevada) | W 50-0 |
| No. 4 Milton (Georgia) | Lanier (Georgia) | W 49-7 |
| No. 5 St. Thomas Aquinas (Florida) | Hollywood Hills (Florida) | W 64-0 |
| No. 6 Duncanville (Texas) | Idle | |
| No. 7 IMG Academy (Florida) | No. 14 Venice (Florida) | W 21-16 |
| No. 8 Archbishop Spalding (Maryland) | St. Mary’s (Maryland) | W 54-0 |
| No. 9 Bergen Catholic (New Jersey) | Idle | |
| No. 10 North Shore (Texas) | Kingwood (Texas) | W 48-21 |
| No. 11 Carrollton (Georgia) | No. 289 Westlake (Atlanta, Georgia) | W 63-27 |
| No. 12 Orange Lutheran (California) | No. 2 St. John Bosco (California) | L 28-24 |
| No. 13 St. Frances Academy (Maryland) | Idle | |
| No. 14 Venice (Florida) | No. 7 IMG Academy (Florida) | L 21-16 |
| No. 15 Lakeland (Florida) | Sumner (Florida) | W 28-0 |
| No. 16 Cocoa (Florida) | No. 37 Norland (Florida) | L 33-14 |
| No. 17 North Crowley (Texas) | Idle | |
| No. 18 Lone Peak (Utah) | No. 139 Skyridge (Utah) | L 21-16 |
| No. 19 Corner Canyon (Utah) | Copper Hills (Utah) | W 49-14 |
| No. 20 DeSoto (Texas) | Idle | |
| No. 21 Miami Central (Florida) | No. 93 Northwestern (Miami, Florida) | W 24-21 |
| No. 22 Mission Viejo (California) | Long Beach Poly (California) | W 49-14 |
| No. 23 Buford (Georgia) | No. 56 Collins Hill (Georgia) | W 34-7 |
| No. 24 Boyle County (Kentucky) | Idle | |
| No. 25 DeMatha (Maryland) | Life Christian Academy (Virginia) | W 35-0 |
| No. 26 Massillon Washington (Ohio) | Clarkson North (Canada) | W 45-6 |
| No. 27 St. Joseph’s Prep (Pennsylvania) | No. 129 La Salle College HS (Pennsylvania) | L 35-34 in 4 OT’s |
| No. 28 Central (Phenix City, Alabama) | No. 213 Auburn (Alabama) | L 38-33 |
| No. 29 East St. Louis (Illinois) | Belleville West (Illinois) | W 63-10 |
| No. 30 DePaul Catholic (New Jersey) | No. 150 Don Bosco Prep (New Jersey) | W 21-20 |
| No. 31 Chaminade-Madonna (Florida) | No. 116 Monarch (Florida) | W 37-8 |
| No. 32 Corona Centennial (California) | Roosevelt (Eastlake, California) | W 63-0 |
| No. 33 North Gwinnett (Georgia) | Peachtree Ridge (Georgia) | W 44-22 |
| No. 34 Atascocita (Texas) | No. 52 Summer Creek (Texas) | W 42-39 |
| No. 35 American Heritage (Plantation, Florida) | Idle | |
| No. 36 JSerra (California) | No. 46 Servite (California) | L 20-7 |
| No. 37 Norland (Florida) | No. 16 Cocoa (Florida) | W 33-14 |
| No. 38 Mill Creek (Georgia) | Dacula (Georgia) | W 54-24 |
| No. 39 Archbishop Hoban (Ohio) | Walsh Jesuit (Ohio) | L 19-14 |
| No. 40 De La Salle (California) | Idle | |
| No. 41 Santa Margarita (California) | No. 1 Mater Dei (California) | L 40-18 |
| No. 42 Mililani (Hawaii) | Campbell (Hawaii) | L 41-20 |
| No. 43 Kahuku (Hawaii) | Waipahu (Hawaii) | W 48-0 |
| No. 44 Clearwater Central Catholic (Florida) | Northside Christian (Florida) | W 42-7 |
| No. 45 Hamilton (Arizona) | Idle | |
| No. 46 Servite (California) | No. 36 JSerra (California) | W 20-7 |
| No. 47 Clay-Chalkville (Alabama) | Mountain Brook (Alabama) | W 21-14 |
| No. 48 Jones (Orlando, Florida) | Idle | |
| No. 49 Folsom (California) | Oak Ridge (California) | W 35-7 |
| No. 50 Saraland (Alabama) | Baldwin County (Alabama) | W 55-7 |
| No. 51 Southlake Carroll (Texas) | Keller (Texas) | W 52-21 |
| No. 52 Summer Creek (Texas) | No. 34 Atascocita (Texas) | L 42-39 |
| No. 53 Weddington (North Carolina) | Idle | |
| No. 54 Riverdale Baptist (Maryland) | Idle | |
| No. 55 Baylor (Tennessee) | No. 157 McCallie (Tennessee) | W 44-12 |
| No. 56 Collins Hills (Georgia) | No. 23 Buford (Georgia) | L 34-7 |
| No. 57 Westlake (Austin, Texas) | Akins (Texas) | W 70-0 |
| No. 58 Good Counsel (Maryland) | Glen Burnie (Maryland) | W 46-8 |
| No. 59 Columbus (Miami, Florida) | Miami (Florida) | W 52-6 |
| No. 60 Mount Carmel (Chicago, Illinois) | Brother Rice (Illinois) | L 16-13 |
| No. 61 Providence Day (North Carolina) | Idle | |
| No. 62 Highland (Arizona) | Red Mountain (Arizona) | L 28-11 |
| No. 63 Grayson (Georgia) | Heritage (Conyers, Georgia) | PPD. |
| No. 64 Imhotep Charter (Pennsylvania) | Northeast (Pennsylvania) | W 48-13 |
| No. 65 Coffee (Georgia) | No. 71 Lee County (Georgia) | Rescheduled 10/11 |
| No. 66 Thompson (Alabama) | No. 195 Hewitt-Trussville (Alabama) | W 15-10 |
| No. 67 Liberty (Arizona) | No. 77 Chandler (Arizona) | W 45-20 |
| No. 68 Denton Guyer (Texas) | No. 112 Coppell (Texas) | L 31-24 |
| No. 69 Ruston (Louisiana) | Stephenville (Texas) | W 63-17 |
| No. 70 St. Edward (Ohio) | St. Ignatius (Ohio) | W 28-6 |
| No. 71 Lee County (Georgia) | No. 65 Coffee (Georgia) | Rescheduled 10/11 |
| No. 72 Aledo (Texas) | No. 272 Denton Ryan (Texas) | W 42-27 |
| No. 73 Brownsburg (Indiana) | Zionsville (Indiana) | W 66-28 |
| No. 74 Rabun Gap-Nacoochee (Georgia) | No. 83 The First Academy (Florida) | W 49-42 |
| No. 75 Basha (Arizona) | No. 165 Brophy Prep (Arizona) | W 35-32 |
| No. 76 Thomas County Central (Georgia) | Veterans (Georgia) | W 61-10 |
| No. 77 Chandler (Arizona) | No. 67 Liberty (Arizona) | L 45-20 |
| No. 78 Westfield (Indiana) | Avon (Indiana) | W 45-13 |
| No. 79 Center Grove (Indiana) | No. 186 Cathedral (Indiana) | L 49-45 |
| No. 80 Oakland (Tennessee) | Siegel (Tennessee) | W 42-7 |
| No. 81 Douglas County (Georgia) | East Coweta (Georgia) | W 42-17 |
| No. 82 Acadiana (Louisiana) | Sulphur (Louisiana) | W 45-0 |
| No. 83 The First Academy (Florida) | No. 74 Rabun Gap-Nacoochee (Georgia) | L 49-42 |
| No. 84 Sierra Canyon (California) | Chaminade (California) | W 42-3 |
| No. 85 Catholic (Baton Rouge, Louisiana) | Idle | |
| No. 86 Atlantic (Delray Beach, Florida) | Treasure Coast (Florida) | W 47-9 |
| No. 87 Mallard Creek (North Carolina) | North Mecklenburg (North Caroilna) | W 49-7 |
| No. 88 Archbishop Moeller (Ohio) | No. 199 Elder (Ohio) | W 42-14 |
| No. 89 Cardinal Hayes (New York) | Kellenburg Memorial (New York) | W 27-7 |
| No. 90 Gainesville (Georgia) | Seckinger (Georgia) | W 41-0 |
| No. 91 Avon (Ohio) | Berea-Midpark (Ohio) | W 49-7 |
| No. 92 Lake Travis (Texas) | Idle | |
| No. 93 Northwestern (Miami, Florida) | No. 21 Miami Central (Florida) | L 24-21 |
| No. 94 Grimsley (North Carolina) | West Guilford (North Carolina) | W 48-0 |
| No. 95 Trinity (Kentucky) | No. 184 St. Xavier (Ohio) | W 7-3 |
| No. 96 Cibolo Steele (Texas) | East Central (San Antonio, Texas) | W 64-59 |
| No. 97 Male (Kentucky) | Douglass (Kentucky) | W 31-28 |
| No. 98 Port Neches-Grove (Texas) | Huntsville (Texas) | W 24-21 |
| No. 99 Roswell (Georgia) | Johns Creek (Georgia) | W 45-0 |
| No. 100 Armwood (Florida) | Plant (Florida) | W 26-0 |
| No. 101 Norcross (Georgia) | Parkview (Georgia) | W 24-0 |
| No. 102 Archbishop Rummel (Louisiana) | Brother Martin (Louisiana) | L 17-13 |
| No. 103 Southridge (Florida) | Edison (Miami, Florida) | W 40-8 |
| No. 104 Westside (Anderson, South Carolina) | Idle | |
| No. 105 Seminole (Sanford, Florida) | Titusville (Florida) | W 33-10 |
| No. 106 North Cobb (Georgia) | Idle | |
| No. 107 John Curtis (Louisiana) | Warren Easton (Louisiana) | W 26-7 |
| No. 108 Glenville (Ohio) | Rhodes (Ohio) | W 35-14 |
| No. 109 Booker T. Washington (Miami, Florida) | Vero Beach (Florida) | L 24-21 |
| No. 110 Palmetto (Miami, Florida) | South Dade (Florida) | W 34-6 |
| No. 111 Northwestern (South Carolina) | Clover (South Caroilna) | W 57-23 |
| No. 112 Coppell (Texas) | No. 68 Denton Guyer (Texas) | W 31-24 |
| No. 113 Belleville (Michigan) | Glenn (Michigan) | W 42-15 |
| No. 114 St. Joseph Regional (Montvale, New Jersey) | Idle | |
| No. 115 Rolesville (North Carolina) | Wakefield (North Carolina) | W 58-7 |
| No. 116 Monarch (Florida) | No. 31 Chaminade-Madonna (Florida) | L 37-8 |
| No. 117 Dutch Fork (South Carolina) | Chapin (South Carolina) | W 63-10 |
| No. 118 Allen (Texas) | Idle | |
| No. 119 Summerville (South Carolina) | Stall (South Caroina) | W 77-6 |
| No. 120 Nease (Florida) | Idle | |
| No. 121 St. Augustine (Florida) | Columbia (Lake City, Florida) | W 25-6 |
| No. 122 Cardinal Ritter (Missouri) | Idle | |
| No. 123 St. Xavier (Kentucky) | Ryle (Kentucky) | W 31-24 |
| No. 124 Arbor View (Nevada) | Desert Pines (Nevada) | W 42-21 |
| No. 125 Lincoln (San Diego, California) | No. 140 Los Alamitos (California) | W 24-14 |
| No. 126 Bryant (Arkansas) | Little Rock Christian (Arkansas) | W 49-0 |
| No. 127 Pittsburg (California) | Los Gatos (California) | W 37-20 |
| No. 128 Owasso (Oklahoma) | No. 276 Union (Oklahoma) | W 48-14 |
| No. 129 La Salle College HS (Pennsylvania) | No. 27 St. Joseph’s Prep (Pennsylvania) | W 35-34 in 4 OT’s |
| No. 130 Christ Presbyterian Academy (Tennessee) | The Webb School (Tennessee) | W 54-6 |
| No. 131 Tampa Bay Tech (Florida) | Idle | |
| No. 132 Zachary (Louisiana) | Opelousas (Louisiana) | W 24-6 |
| No. 133 Oaks Christian (California) | Pacifica (California) | W 42-20 |
| No. 134 Camden County (Georgia) | No. 147 Valdosta (Geoergia) | L 56-37 |
| No. 135 Serra (Gardena, California) | Loyola (Los Angeles, California) | W 42-35 |
| No. 136 Leuzinger (California) | No. 271 Inglewood (California) | L 34-29 |
| No. 137 Timpview (Utah) | Wasatch (Utah) | W 48-14 |
| No. 138 University Lab (Baton Rouge, Louisiana) | St. Paul’s (Louisiana) | W 29-12 |
| No. 139 Skyridge (Utah) | No. 18 Lone Peak (Utah) | W 21-16 |
| No. 140 Los Alamitos (California) | No. 125 Lincoln (San Diego, California) | L 24-14 |
| No. 141 Lehi (Utah) | Westlake (Utah) | W 48-7 |
| No. 142 Cherry Creek (Colorado) | Cherokee Trail (Colorado) | W 45-0 |
| No. 143 Conway (Arkansas) | North Little Rock (Arkansas) | W 63-7 |
| No. 144 Malvern Prep (Pennsylvania) | Idle | |
| No. 145 Delbarton (New Jersey) | Pope John XXIII (New Jersey) | W 35-34 |
| No. 146 American Leadership Academy (Queen Creek, Arizona) | Mountain Pointe (Arizona) | W 17-0 |
| No. 147 Valdosta (Georgia) | No. 134 Camden Conty (Georgia) | W 56-37 |
| No. 148 South Oak Cliff (Texas) | Hillcrest (Texas) | W 36-0 |
| No. 149 Colquitt County (Georgia) | No. 160 Lowndes (Georgia) | W 38-35 |
| No. 150 Don Bosco Prep (New Jersey) | No. 30 DePaul Catholic (New Jersey) | L 21-20 |
| No. 151 Iona Prep (New York) | St. Anthony’s (Melville, New York) | W 48-40 |
| No. 152 Benedictine (Georgia) | No. 201 Warner Robins (Georgia) | W 35-21 |
| No. 153 Lincoln-Way East (Illinois) | Neuqua Valley (Illinois) | W 48-14 |
| No. 154 Langston Hughes (Georgia) | McIntosh (Georgia) | W 49-0 |
| No. 155 Katy (Texas) | Idle | |
| No. 156 Ravenwood (Tennessee) | Summit (Tennessee) | W 45-0 |
| No. 157 McCallie (Tennessee) | No. 55 Baylor (Tennessee) | L 44-12 |
| No. 158 Detroit Catholic Central (Michigan) | Brother Rice (Michigan) | W 37-14 |
| No. 159 Gadsden County (Florida) | No. 282 Lincoln (Tallahassee, Florida) | W 31-21 |
| No. 160 Lowndes (Georgia) | No. 149 Colquitt County (Georgia) | L 38-35 |
| No. 161 Toledo Central Catholic (Ohio) | St. John’s Jesuit (Ohio) | W 56-21 |
| No. 162 Manatee (Florida) | Idle | |
| No. 163 Edna Karr (Louisiana) | St. Augustine (Louisiana) | W 27-7 |
| No. 164 Dr. Phillips (Florida) | Idle | |
| No. 165 Brophy Prep (Arizona) | No. 75 Basha (Arizona) | W 35-32 |
| No. 166 Murrieta Valley (California) | Norco (California) | W 42-27 |
| No. 167 Lake Mary (Florida) | North Miami Beach (Florida) | W 42-7 |
| No. 168 Texas (Texasarkana, Texas) | Whtehouse (Texas) | W 51-10 |
| No. 169 Fayetteville (Arkansas) | Rogers (Arkansas) | W 41-38 |
| No. 170 Hough (North Carolina) | Idle | |
| No. 171 Christian Brothers College (Missouri) | Lipscomb Academy (Tennessee) | W 37-23 |
| No. 172 Phoebus (Virginia) | Hampton (Virginia) | W 37-3 |
| No. 173 Bradford (Florida) | Palatka (Florida) | W 41-0 |
| No. 174 Maury (Virginia) | Norcom (Virginia) | W 49-12 |
| No. 175 Lake Wales (Florida) | Idle | |
| No. 176 Highland Park (Texas) | Red Oak (Texas) | W 32-14 |
| No. 177 Vanguard (Florida) | North Marion (Florida) | W 41-2 |
| No. 178 Mandarin (Florida) | Rockledge (Florida) | W 24-7 |
| No. 179 Clovis North (California) | No. 290 Central (Fresno. California) | W 26-21 |
| No. 180 Cardinal Gibbons (North Carolina) | Athens Drive (North Carolina) | W 57-7 |
| No. 181 Walton (Georgia) | Marrieta (Georgia) | W 21-3 |
| No. 182 Edgewater (Florida) | Idle | |
| No. 183 Lakota West (Ohio) | Sycamore (Ohio) | W 52-0 |
| No. 184 St. Xavier (Ohio) | No. 95 Trinity (Kentucky) | L 7-3 |
| No. 185 Roman Catholic (Pennsylvania) | Cardinal O’Hara (Pennsylvania) | W 52-34 |
| No. 186 Cathedral (Indiana) | No. 79 Center Grove (Indiana) | W 49-42 |
| No. 187 Gonzaga (Washington, DC) | Benedictine (Virginia) | W 23-16 |
| No. 188 Raines (Florida) | Ribault (Florida) | W 52-12 |
| No. 189 Bixby (Oklahoma) | Moore (Oklahoma) | W 49-7 |
| No. 190 Fort Bend Hightower (Texas) | Fort Bend Dulles (Texas) | W 56-0 |
| No. 191 Winton Woods (Ohio) | Loveland (Ohio) | W 49-0 |
| No. 192 Longview (Texas) | No. 242 Rockwall (Texas) | W 63-34 |
| No. 193 Euless Trinity (Texas) | Idle | |
| No. 194 Byron Nelson (Texas) | Timber Creek (Texas) | W 27-7 |
| No. 195 Hewitt-Trussville (Alabama) | No. 66 Thompson (Alabama) | L 15-10 |
| No. 196 St. John’s College HS (Washington, DC) | Cornerstone Christian (San Antonio, Texas) | W 17-9 |
| No. 197 De Smet (Missouri) | Chaminade (Missouri) | W 44-7 |
| No. 198 Bolles School (Florida) | Columbia (Lake City, Florida) | W 42-17 |
| No. 199 Elder (Ohio) | No. 88 Archbishop Moeller (Ohio) | L 42-14 |
| No. 200 Perry (Arizona) | Idle | |
| No. 201 Warner Robins (Georgia) | No. 152 Benedictine (Georgia) | L 35-21 |
| No. 202 Blanche Ely (Florida) | No. 273 Plantation (Florida) | W 18-16 |
| No. 203 Vandegrift (Texas) | McNeil (Texas) | W 28-0 |
| No. 204 Houston County (Georgia) | Northside (Warner Robins, Georgia) | W 63-22 |
| No. 205 Maryville (Tennessee) | Bearden (Tennessee) | W 53-43 |
| No. 206 Bishop Chatard (Indiana) | Andrean (Indiana) | W 39-14 |
| No. 207 Dripping Springs (Texas) | Austin (Texas) | W 49-7 |
| No. 208 Brentwood (Tennessee) | Franklin (Tennessee) | W 17-9 |
| No. 209 Prosper (Texas) | Rock Hill (Texas) | W 49-7 |
| No. 210 Westfield (Texas) | Dekaney (Texas) | W 35-14 |
| No. 211 Alexandria (Louisiana) | Many (Louisiana) | W 69-7 |
| No. 212 Eau Gallie (Florida) | Idle | |
| No. 213 Auburn (Alabama) | No. 28 Central (Phenix City, Alabama) | W 38-33 |
| No. 214 Rockhurst (Missouri) | Blue Springs (Missouri) | L 30-13 |
| No. 215 St. Mary’s (Stockton, California) | Lodi (California) | W 63-0 |
| No. 216 Parkview (Arkansas) | De Queen (Arkansas) | W 66-7 |
| No. 217 San Ramon Valley (California) | Granada (California) | W 35-6 |
| No. 218 Alcoa (Tennessee) | West (Knoxville, Tennessee) | W 28-10 |
| No. 219 Richmond Hill (Georgia) | Tift County (Georgia) | W 21-17 |
| No. 220 St. Ignatius College Prep (California) | Archbishop Riordan (California) | W 31-28 |
| No. 221 Serra (San Mateo, California) | Sacred Heart Cathedral Prep (California) | W 29-12 |
| No. 222 Creekside (Georgia) | Pace Academy (Georgia) | W 49-0 |
| No. 223 Destrehan (Louisiana) | Terrebonne (Louisiana) | L 30-21 |
| No. 224 Rocklin (California) | Whitney (California) | W 42-0 |
| No. 225 Olentangy Liberty (Ohio) | No. 234 Upper Arlington (Ohio) | L 31-28 |
| No. 226 Granite Hills (El Cajon, California) | Steele Canyon (California) | W 39-0 |
| No. 227 Ensworth (Tennessee) | First Baptist Academy (Naples, Florida) | W 35-0 |
| No. 228 Buchholz (Florida) | Gainesville (Florida) | PPD in 2nd Qt. Buchholz leading 21-7 |
| No. 229 Jesuit (Florida) | No. 257 University (Orange City, Florida) | L 35-33 |
| No. 230 Cartersville (Georgia) | Cass (Georgia) | W 38-7 |
| No. 231 Springfield (Ohio) | Wayne (Huber Heights, Ohio) | L 36-6 |
| No. 232 Pickerington North (Ohio) | Central Crossing (Ohio) | W 42-0 |
| No. 233 Neville (Louisiana) | Sterlington (Louisiana) | W 17-10 |
| No. 234 Upper Arlington (Ohio) | No. 225 Olentangy Liberty (Ohio) | W 31-28 |
| No. 235 Anderson County (Tennessee) | Clinton (Tennessee) | W 40-7 |
| No. 236 Cary-Grove (Illinois) | Hampshire (Illinois) | W 48-7 |
| No. 237 Rancho Cucamonga (California) | Upland (California) | W 10-7 |
| No. 238 Lone Star (Frisco, Texas) | Frisco (Texas) | W 27-24 |
| No. 239 Gaffney (South Carolina) | Eastside (Taylors, South Carolina) | Cancelled |
| No. 240 Davison (Michigan) | East Lansing (Michigan) | W 35-10 |
| No. 241 Chaparral (Temecula, California) | Vista Murrieta (California) | W 55-28 |
| No. 242 Rockwall (Texas) | No. 192 Longview (Texas) | L 63-34 |
| No. 243 Brentwood Academy (Tennessee) | Innovation Academy (Tennessee) | W 52-0 |
| No. 244 Lewisville (Texas) | Braswell (Texas) | W 56-23 |
| No. 245 C.E. King (Texas) | Goose Creek Memorial (Texas) | W 48-0 |
| No. 246 Crest (North Carolina) | South Point (North Carolina) | L 27-26 |
| No. 247 Blessed Trinity (Georgia) | Kell (Georgia) | W 31-21 |
| No. 248 Willis (Texas) | College Park (Texas) | W 45-21 |
| No. 249 Hattiesburg (Mississippi) | George County (Mississippi) | W 48-21 |
| No. 250 Piper (Florida) | Boyd Anderson (Florida) | W 34-12 |
| No. 251 The Woodlands (Texas) | Idle | |
| No. 252 Tupelo (Mississippi) | West Point (Missisippi) | W 35-14 |
| No. 253 Carl Albert (Oklahoma) | El Reno (Oklahoma) | W 70-0 |
| No. 254 Chaminade (New York) | Archbishop Stepinac (New York) | Sunday |
| No. 255 Marist (Georgia) | North Springs (Georgia) | W 48-0 |
| No. 256 Enterprise (Alabama) | No. 283 Carver Montgomery (Alabama) | W 17-14 |
| No. 257 University (Orange City, Florida) | No. 229 Jesuit (Florida) | W 35-33 |
| No. 258 Argyle (Texas) | Everman (Texas) | W 63-14 |
| No. 259 Teurlings Catholic (Louisiana) | Comeaux (Louisiana) | W 48-13 |
| No. 260 De La Salle Collegiate (Michigan) | Idle | |
| No. 261 Pulaski Academy (Arkansas) | Central (Little Rock, Arkansas) | W 63-14 |
| No. 262 Anderson (Ohio) | Turpin (Ohio) | W 56-13 |
| No. 263 West Orange (Florida) | Evans (Florida) | L 39-13 |
| No. 264 Dickinson (Texas) | Clear Lake (Texas) | W 35-22 |
| No. 265 Cardinal Newman (Florida) | Goleman (Florida) | W 21-6 |
| No. 266 Madison-Ridgeland Academy (Missisisippi) | East Rankin Academy (Mississippi) | W 44-14 |
| No. 267 Apopka (Florida) | Idle | |
| No. 268 Cardinal Mooney (Florida) | Lakewood (Florida) | W 40-16 |
| No. 269 Bishop Verot (Florida) | Idle | |
| No. 270 Fulshear (Texas) | Alief Hastings (Texas) | W 65-27 |
| No. 271 Inglewood (California) | No. 136 Leuzinger (California) | W 34-29 |
| No. 272 Denton Ryan (Texas) | No. 72 Aledo (Texas) | L 42-27 |
| No. 273 Plantation (Florida) | No. 202 Blanche Ely (Florida) | L 18-16 |
| No. 274 Ridge Point (Texas) | Fort Bend Bush (Texas) | W 70-0 |
| No. 275 West Jones (Mississippi) | Jackson Prep (Mississippi) | L 42-7 |
| No. 276 Stillwater (Oklahoma) | Grant (Oklahoma) | W 65-0 |
| No. 277 Union (Oklahoma) | No. 128 Owasso | L 48-14 |
| No. 278 Spain Park (Alabama) | Pelham (Alabama) | |
| No. 279 Gaither (Florida) | Idle | |
| No. 280 Whitehaven (Tennessee) | Germantown (Tennessee) | L 24-20 |
| No. 281 Parker (Birmingham, Alabama) | Jackson-Olin (Alabama) | W 56-0 |
| No. 282 Buchanan (Clovis, California) | Clovis (California) | L 37-10 |
| No. 283 Lincoln (Tallahassee, Florida) | No. 159 Gadsden County (Florida) | L 31-21 |
| No. 284 (tied) Hoover (Alabama) | Oak Mountain (Alabama) | W 28-10 |
| No. 284 (tied) Carver Montgomery (Alabama) | No. 256 Enterprise (Alabama) | L 17-14 |
| No. 286 Niceville (Florida) | Idle | |
| No. 287 Charlotte Catholic (North Carolina) | Rocky River (North Caroina) | W 28-6 |
| No. 288 Permian (Texas) | Idle | |
| No. 289 Independence (North Carolina) | Garinger (North Carolina) | W 61-7 |
| No. 290 Westlake (Atlanta, Georgia) | No. 11 Carrollton (Georgia) | L 63-27 |
| No. 291 Central (Fresno, California) | Clovis North (California) | L 26-21 |
| No. 292 Bridgeland (Texas) | Cypress Springs (Texas) | W 18-6 |
| No. 293 Father Ryan (Tennessee) | Memphis University School (Tennessee) | W 27-21 |
| No. 294 Westgate (Louisiana) | St. Thomas More (Louisiana) | l 48-6 |
| No. 295 Pine-Richland (Pennsylvania) | Penn Hills (Pennsylvania) | W 31-21 |
| No. 296 Montgomery Bell Academy (Tennessee) | Knoxville Catholic (Tennessee) | W 23-23 |
| No. 297 Pearl-Cohn (Tennessee) | Whites Creek (Tennessee) | W 44-6 |
| No. 298 Houston (Tennessee) | Bartlett (Tennessee) | W 33-14 |
| No. 299 West Broward (Florida) | Idle | |
| No. 300 Cardinal Gibbons (Florida) | Hallandale (Florida) | W 28-6 |
